lactam /lac·tam/ (lak´tam) a cyclic amide formed from aminocarboxylic acids by elimination of water; lactams are isomeric with lactims, which are enol forms of lactams. 
lactam
)
β-lactam see under antibiotic.
lac·tam (l k tm )n. An amide formed from amino carboxylic acids containing a keto group in a ring configuration, as seen in purines, pyrimidines, and antibiotics. It is tautomeric to lactim. |
lactam
[lak′təm]
a cyclic amide created by the elimination of a molecule of water from aminocarboxylic acid. Lactim is the isomeric form of lactam.
lactam
a cyclic amide formed from aminocarboxylic acids by elimination of water; lactams are isomeric with lactims, which are enol forms of lactams.
β-lactam antibiotics
includes the penicillins, cephalosporins, carbapenems and penems. See also β-lactam ring (below).
β-lactam ring
an integral part of the formula of β-lactam antibiotics. Disruption of the ring by β-lactamase produced by some bacteria, e.g. Escherichia coli, Bacillus anthracis, destroys the antimicrobial activity of the compound.
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