cyclodextrin

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cyclodextrin

(sī-klō-dĕks′trĭn)
A molecule made of linked dextrose subunits that can be used in drug delivery in the body. Cyclodextrins have lipid centers surrounded by water-soluble exteriors. This combination allows fat-soluble medicines to be carried through the bloodstream to lipid-rich organs like the brain.
References in periodicals archive ?
We also found that gamma-cyclodextrins were more successful than beta-cyclodextrins and were more cost-effective," Schmidt said.
Based on previous literature findings that described collagen fibrils (5-7) and beta-cyclodextrins (8-14), computer-assisted three-dimensional scale models of collagen segments and anticipated examples of beta-cyctodextrin's poiymerizabie derivatives were prepared and studied.
The many NMR spectra obtained with the starting reagents and reaction products were all in accord with relevant information obtained from reference texts, with literature relating to beta-cyclodextrins, and with the MALDI analytic findings.
The CAPTISOL drug delivery technology arises from sulfobutylether beta-cyclodextrins originally synthesized and patented by scientists at the University of Kansas Higuchi Biosciences Center for Drug Delivery Research.
Especially costly is gamma-cyclodextrin with a "donut hole" larger than those of alpha- and beta-cyclodextrins.
If these results are replicated in future human clinical trials, the sulfated beta-cyclodextrins might have an important role to play in combating this all-too-common problem.
CyDex was established to license, develop and commercialize a series of anionically charged sulfobutylether beta-cyclodextrins originally synthesized and patented by scientists from the University of Kansas Higuchi Biosciences Center for Drug Delivery Research -- including CAPTISOL.
a privately owned company located in Overland Park, Kansas, was established to license, develop and commercialize a series of anionically charged sulfobutylether beta-cyclodextrins.
a privately owned company located in Overland Park, Kansas, was established to license, develop and commercialize a series of anionically charged sulfobutylether beta-cyclodextrins originally synthesized and patented by scientists from the University of Kansas Higuchi Biosciences Center for Drug Delivery Research for use in drug development and formulation.
a privately owned company located in Overland Park, Kansas, was established to license, develop and commercialize a series of anionically charged sufobutylether beta-cyclodextrins originally synthesized and patented by scientists from the University of Kansas Higuchi Biosciences Center for Drug Delivery Research for use in drug development and formulation.
and Peptichemio, AG today announced the signing of a licensing agreement granting Peptichemio worldwide rights to CyDex's CAPTISOL(R) sulfobutylether beta-cyclodextrin (SBE-beta-CD) drug delivery technology for Peptichemio's unique anticancer compound.
NYSE: AGN), today announced the signing of a licensing agreement granting Allergan worldwide exclusive rights to CyDex's CAPTISOL(R) sulfobutylether beta-cyclodextrin (SBE-B-CD) drug delivery technology for specific ophthalmic uses.