PPBP

(redirected from Beta-TG)

PPBP

A gene on chromosome 4q12-q13 that encodes a platelet-derived growth factor of the CXC chemokine family, which is a potent chemoattractant and activator of neutrophils. PPBP drives various cellular processes, including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells.
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These individuals showed a more than sevenfold increase in beta-TG on one morning.
and noon on two days no more than one week apart, she and her colleagues assayed beta-TG levels in 19 men and 10 women.
Morning beta-TG levels averaged more than 2 1/2 times higher on the day the group skipped breakfast.