DC (commonly known as Tree turmeric or Indian Barberry) has previously demonstrated beneficial effects in dyslipidaemia with significant reductions in total cholesterol (TC) and low-density lipoprotein (LDL) cholesterol attributed to up-regulation of LDL-receptor expression.
In particular, Berberis aristata acts up-regulating LDL-receptor (LDL-R) expression independent of sterol regulatory element binding proteins, but dependent on extracellular signal-regulated kinases (ERK) and c-Jun N-terminal kinase (JNK) activation leading to total cholesterol (TC) and LDL-C reduction of about 30 and 25%, respectively (Kong et al.
588 mg of hydro-ethanolic extract from cortex arboris of Berberis aristata DC.
The batches of dispensed nutraceutical were TJ808 (containing Silymarin batch 20120604TH and Berberis aristata batch 01206168) and LJ665 (containing Silymarin batch 20120609TH and Berberis aristata batch 01201037).
The positive effects of Berberis aristata on lipid profile were already reported by our group, in a study previously published where Berberol[R] reduced lipid profile compared to placebo; in particular, we recorded a TC reduction of 23.
22], reported that Berberis aristata
roots contain 3.
Of 132 medicinal plant species the following 22 are considered rare and endangered; Aconitum atrox, Dactylorhiza hatagirea, Fritillaria roylei, Thalictrum foliolosum, Berberis aristata
, Artemisia maritime, Delphinium cashmerianum, Gloriosa superb, Saussurea obvallata, Betula utilis, Nardostachys jatamansi, Swertia chiraita, Rheum austral, Rheum webbianum, Podophylum hexandrum, Hippophea salicifolia, Bergenia ligulata, Bergenia stracheyi, Arnebia benthamii, Rhododendron arboretum, Aegle marmelos, Lyonia ovalifolia and Waldhemia glabra.
Berberine, sourced from Berberis aristata
roots, shows significant anti-microbial activity when evaluated against the oral pathogens Streptococcus mutatis and Fusobacterium nucleatum, Mr.
The study investigating the effect of Berberis aristata
and Silybum marianum (Berberol) in combination in dyslpidaemic patients with intolerance to high dose statins found:
Berberine is identified as an active component in the roots, rhizome, and stem bark of Berberis vulgaris (barberry), Berberis aguifolium (Oregon grape), Berberis aristata
(tree turmeric), and Tinospora cordifolia (Craig, 1999).
Berberine is an isoquinoline derivative alkaloid that has been isolated from Berberis aquifolium (Oregon grape), Berberis aristata
(tree turmeric), Berberis vulgaris (barberry), and Hydrastis canadensis (goldenseal) (Ikram, 1975).