azole

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pyr·role

(pir'ōl),
Divinylenimine; a heterocyclic compound found in many biologically important substances, for example, heme.
Synonym(s): azole, imidole

azole

(ăz′ōl′, ā′zōl′)
n.
Any of a class of organic compounds that have a five-membered heterocyclic ring with at least one nitrogen and two double bonds and that also may contain another heteroatom.

azole

Any of a family of broad-spectrum antifungals, including ketoconazole, fluconazole and itraconazole.
 
Indications
Blastomyocosis, candidiasis, coccidioidomycosis, cryptococcosis, histoplasmosis, paracoccidoidomycosis and in sporotrichosis.
 
Adverse effects
Nausea, vomiting, anorexia, rash, pruritus, nonspecific increased liver enzymes, anaemia, leukopenia, thrombocytopenia, headache and others.
 
Drug interactions
Plasma levels of azoles are decreased by antacids, H2-receptor antagonists, sucralfate, isoniazid, phenytoin and rifampin.

azole

Infectious disease One of a family of synthetic broad-spectrum antifungal antibiotics–including ketoconazole, fluconazole, itraconazole Indications Various azoles have established efficacy in treating blastomyocosis, candidiasis, coccidioidomycosis, cryptococcosis, histoplasmosis, paracoccidoidomycosis and sporotrichosis Adverse effects N&V, anorexia, rash, pruritus, nonspecific ↑ liver enzymes, anemia, leukopenia, thrombocytopenia, headache, etc Drug interactions Plasma levels of azoles are ↓ by antacids, H2-receptor antagonists, sucralfate, isoniazid, phenytoin, rifampin. See Fluconazole, Itraconazole, Ketoconazole.

pyr·role

(pir'ōl)
A heterocyclic compound found in many biologically important substances.
Synonym(s): azole, imidole.