imidazole

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imidazole

 [im″id-az´ōl]
1. an organic compound in which two of the five atoms that make up the ring are nitrogen atoms. It is an antimetabolite and inhibitor of histamine and is used as an insecticide.
2. any of a class of antifungal agents that contain this compound.

im·id·a·zole

(im-id'ă-zōl),
A five-membered heterocyclic compound occurring in l-histidine and other biologically important compounds.

imidazole

/im·id·az·ole/ (im″id-az´ōl)
1. a heterocyclic organic compound in which two of five ring atoms are nitrogen; used as an insecticide.
Imidazole.
2. any of a class of antifungal compounds containing this structure.

imidazole

(ĭm′ĭ-dăz′ōl′)
n.
1. An organic crystalline base, C3H4N2, that is an inhibitor of histamine.
2. Any of various derivatives of this compound, which often have antifungal, anthelmintic, or antibiotic properties.

im·id·a·zole

(i-mid'i-zōl)
A five-membered heterocyclic compound occurring in l-histidine and other biologically important compounds.
References in periodicals archive ?
For example, in the 1H-NMR spectrum of 1-ethyl gallate-2-bromine phenoxymethyl benzimidazoles (8h), the two single peaks at 9.
Clastogenic and aneugenic effects of three benzimidazole derivatives in the in vitro micronucleus test using human lymphocytes.
Longterm serological evaluation of patients with cystic echinococcosis treated with benzimidazole carbamates.
2003), lo que hace necesario realizar rotacion o alternancia de aplicaciones con fungicidas de diferentes mecanismos de accion; por ejemplo, la aparicion de poblaciones con mayor tolerancia a los benzimidazoles y triazoles en los ultimos anos ha determinado un incremento del uso de clorotalonil en aspersiones acuosas, debido a que esta molecula tiene multiples sitios de accion y es mas dificil que el patogeno evolucione resistencia hacia ella (Perez, 2006).
This structure will guide approaches to rationally design better drug candidates and improve the known benzimidazole inhibitors," said Hermann.
Variability and variation in drug susceptibility among Giardia duodenalis isolates and clones exposed to 5-nitromidazoles and benzimidazoles in vitro.
Albendazole is an antihelmintic drug belong to the benzimidazoles group, which binds nematode tubulin inhibiting the polymerization of microtubules, which are subsequently unable to transport secretory granules or secrete enzymes within the cell cytoplasm; this eventually results in cell lysis and helminth paralysis [9, 20].
Benzimidazoles (BZs) are also preferred drugs in human mass chemotherapy programmes due to their low cost, broad spectrum of activity, relative high efficacy, and ease of administration (5).
Some examples of classes of organic compounds used in OSPs are benzotriazoles, benzimidazoles, alkyl benzimidazoles and aryl-phenylbenzimidazoles.
Resistance to benzimidazoles usually requires only a single mutation in a single gene.
The benzimidazoles are rapidly metabolized in birds by the liver and cytochrome P-450 system.