benserazide

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benserazide

 [ben-ser´ah-zīd]
an inhibitor of the decarboxylation of peripheral levodopa to dopamine, having actions similar to those of carbidopa. When given with levodopa, benserazide produces higher brain concentrations of dopamine with lower doses of levodopa, thus lessening the side effects seen with higher doses. It is used orally, in conjunction with levodopa, as an antiparkinsonian agent.

ben·ser·a·zide

(ben-ser'ă-zīd),
An l-aromatic amino acid decarboxylase (dopa decarboxylase) inhibitor resembling carbidopa in action; given in combination with levodopa as an antiparkinsonian regimen. The benserazide prevents peripheral destruction of levodopa and thus reduces cardiovascular side effects of treatment.

benserazide

/ben·ser·a·zide/ (ben-ser´ah-zīd) an inhibitor of decarboxylation of levodopa in extracerebral tissues, used in combination with levodopa as an antiparkinsonian agent.

benserazide

[ben-ser′ah-zīd]
an inhibitor of the decarboxylation of peripheral levodopa to dopamine, having actions similar to those of carbidopa. When given with levodopa, benserazide produces higher brain concentrations of dopamine with lower doses of levodopa, thus lessening the side effects seen with higher doses. It is used orally in conjunction with levodopa as an antiparkinsonian agent.

benserazide

A dopamine precursor drug given in conjunction with LEVODOPA in the treatment of PARKINSON'S DISEASE to prevent the breakdown of levodopa in the body. A brand name is Madopar.
References in periodicals archive ?
It is usually administered with benzerazide or carbidopa, or a combination of carbidopa and entacapone, which delays the premature conversion of L-Dopa to dopamine in peripheral tissues.