benzalkonium chloride

(redirected from Benzalkonium)
Also found in: Dictionary, Encyclopedia, Wikipedia.

benzalkonium chloride

 [ben″zal-ko´ne-um]
a quaternary ammonium compound used as a surface disinfectant and detergent, topical antiseptic, and antimicrobial preservative.

ben·zal·ko·ni·um chlo·ride

(ben'zal-kō'nē-ŭm klōr'īd),
A mixture of alkylbenzyldimethylammonium chlorides in which the alkyls are long-chain compounds (C8 to C18); a surface-active germicide for many pathogenic nonsporulating bacteria and fungi. Aqueous solutions of this agent have a low surface tension, and possess detergent, keratolytic, and emulsifying properties that aid penetration and wetting of tissue surfaces.

benzalkonium chloride

/ben·zal·ko·ni·um chlo·ride/ (ben″zal-ko´ne-um) a quaternary ammonium compound used as a surface disinfectant and detergent, topical antiseptic, and antimicrobial preservative.

benzalkonium chloride

(bĕn′zăl-kō′nē-əm)
n.
A yellow-white powder prepared in an aqueous solution and used as a detergent, fungicide, bactericide, and spermicide.

benzalkonium chloride

a disinfectant and fungicide prepared in an aqueous solution in various strengths.

benzalkonium chloride

An antiseptic used in solution for skin and wound cleansing, as a means of sterilizing eye drops and contact lens solutions and as an ingredient in throat lozenges. Allergic reactions occur. Benzalkonium is included in Bradosol lozenges and, for external use only, in Conotrane, Dermol, Drapolene, Emulsiderm and Oilatum Plus.

antiseptic 

An agent that kills or prevents the growth of bacteria. This term is generally restricted to agents that are sufficiently non-toxic for superficial application to living tissues. These include the preservatives for eye drops and contact lens solutions. Examples of antiseptics are alcohol, benzalkonium chloride, cetrimide, chlorbutanol, chlorhexidine, hydrogen peroxide, thimerosal (or thiomersalate). Other agents that are too toxic to be applied to living tissues are called disinfectants and are used to sterilize instruments and apparatus. See disinfection; ethylenediamine tetraacetic acid; neutralization; sterilization.

benzalkonium chloride

a quaternary ammonium compound used as a surface disinfectant and detergent and as a topical antiseptic and antimicrobial preservative. See also zephiran.
References in periodicals archive ?
For international and China market analysis, the report analyzes Benzalkonium Chloride markets in China and other countries or regions (such as US, Europe, Japan, etc.
Safety and acceptability of vaginal disinfection with benzalkonium chloride in HIV infected pregnant women in west Africa: ANRS 049b phase II randomized, double blinded placebo controlled trial.
The committee said camphor benzalkonium methosulphate is safe as a UV filter at concentrations of up to 6% in cosmetic sun preparations, however because of its "borderline margin of safety, its use in other cosmetics products is not recommended".
Britz and Maibach (15) found that vulvar skin was significantly more reactive than forearm skin to benzalkonium chloride and maleic acid, but Elsner et al (16) found that the vulva was slightly less reactive than the forearm to low concentrations of sodium lauryl sulfate (SLS).
The problem appears to be related to the surfactant properties of benzalkonium chloride.
Proposed mechanisms for the paradoxical bronchospastic effect of albuterol include bronchospasm secondary to other compounds in the albuterol preparations such as benzalkonium chloride (used as a preservative in nebulizer solutions), (5) chlorofluorocarbons (used as propellants in metered dose inhalers), (5) and oleic acid (used as a dispersant in MDIs), (5) and the presence of (S)-albuterol in racemic preparations of albuterol.
The product contains four different antivirus components ethanol, benzalkonium chloride, polyoxyethylene alkylamine and polyhexamethylene biguanide (PHMB), and can remove not only general bacteria and viruses but also noroviruses that cause a fatal food poisoning.
The lack of effect of benzalkonium chloride on the cilia of the nasal mucosa in patients with perennial allergic rhinits: a combined functional, light, scanning and transmission electron microscopy study.
The seven chemical mixtures tested were 15% sodium carbonate, 45% potassium carbonate, 12% trisodium phosphate, 12% magnesium hydroxide, 50% magnesium hydroxide, 45% calcium hydroxide and a mixture of 15% sodium carbonate and 7,000 ppm benzalkonium chloride.
Benzalkonium (BAK) chloride is a known quaternary ammonium bactericide.
Second, although not proved efficacious against cutaneous chytridiomycosis, the use of benzalkonium chloride, a recognized therapy for infections with non-hyphal fungi, failed to reduce mortality rates.
In addition, spermicides containing other active ingredients, such as octoxynol-9, benzalkonium chloride and menfegol, are also distributed in developed and developing countries.