benzalkonium chloride

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benzalkonium chloride

 [ben″zal-ko´ne-um]
a quaternary ammonium compound used as a surface disinfectant and detergent, topical antiseptic, and antimicrobial preservative.

ben·zal·ko·ni·um chlo·ride

(ben'zal-kō'nē-ŭm klōr'īd),
A mixture of alkylbenzyldimethylammonium chlorides in which the alkyls are long-chain compounds (C8 to C18); a surface-active germicide for many pathogenic nonsporulating bacteria and fungi. Aqueous solutions of this agent have a low surface tension, and possess detergent, keratolytic, and emulsifying properties that aid penetration and wetting of tissue surfaces.

benzalkonium chloride

/ben·zal·ko·ni·um chlo·ride/ (ben″zal-ko´ne-um) a quaternary ammonium compound used as a surface disinfectant and detergent, topical antiseptic, and antimicrobial preservative.

benzalkonium chloride

(bĕn′zăl-kō′nē-əm)
n.
A yellow-white powder prepared in an aqueous solution and used as a detergent, fungicide, bactericide, and spermicide.

benzalkonium chloride

a disinfectant and fungicide prepared in an aqueous solution in various strengths.

benzalkonium chloride

An antiseptic used in solution for skin and wound cleansing, as a means of sterilizing eye drops and contact lens solutions and as an ingredient in throat lozenges. Allergic reactions occur. Benzalkonium is included in Bradosol lozenges and, for external use only, in Conotrane, Dermol, Drapolene, Emulsiderm and Oilatum Plus.

antiseptic 

An agent that kills or prevents the growth of bacteria. This term is generally restricted to agents that are sufficiently non-toxic for superficial application to living tissues. These include the preservatives for eye drops and contact lens solutions. Examples of antiseptics are alcohol, benzalkonium chloride, cetrimide, chlorbutanol, chlorhexidine, hydrogen peroxide, thimerosal (or thiomersalate). Other agents that are too toxic to be applied to living tissues are called disinfectants and are used to sterilize instruments and apparatus. See disinfection; ethylenediamine tetraacetic acid; neutralization; sterilization.

benzalkonium chloride

a quaternary ammonium compound used as a surface disinfectant and detergent and as a topical antiseptic and antimicrobial preservative. See also zephiran.
References in periodicals archive ?
Pharmacological modification of the epithelial permeability by benzalkonium chloride in UVA/Riboflavin corneal collagen cross-linking.
Only the strong irritant benzalkonium chloride was found to be false-positive regarding CD54.
Proparacaine contains benzalkonium chloride and EDTA as preservative agents, and both compounds also function as drug penetration enhancers.
Benzalkonium chloride (BAC), the most commonly used preservative in anti-glaucoma eye drops, is largely responsible for the toxicity.
Compared with the cmc and cmc of benzalkonium chloride including dodecyldimethylbenzyl ammonium chlorides (BC12), tetradecyldimethylbenzyl ammonium chlorides (BC14) and hexadecyldimethylbenzyl ammonium chlorides (BC16) that reported by Farias and Gracia, et al [22-24], we could know the surface activity of ADMDHAC in aqueous solution was the best one among BC12, BC14, BC16 and ADMDHAC.
Benzalkonium interference with test methods for potassium and sodium.
Identification of benzalkonium chloride in commercial grapefruit seed extracts.
A large body of evidence has indicated that ocular preservatives, particularly benzalkonium chloride (BAK), impair surface tissues of the eye leading to inflammation, dry eye and other issues," explained Penny Asbell, M.
Use of household cleaning products that contain benzalkonium chloride may decrease the susceptibility of bacteria to other antimicrobial ingredients in cleaning products and increase their resistance to antibiotics, according to the results of a randomized, double-blind study.
This is the first randomized intervention study to assess the relationship between two biocidal ingredients found in household cleaning products benzalkonium chloride (BZK) and triclosan--and antibiotic resistance in the household setting, Allison E.
19) randomly assigned HIV-infected pregnant women in Cote d'Ivoire and Burkina Faso to either 1% benzalkonium chloride or placebo using a computer-generated system by block-randomisation.