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benzalkonium chloride
(redirected from Benzalkonium)

   Also found in: Encyclopedia, Wikipedia 0.02 sec.
benzalkonium chloride /ben·zal·ko·ni·um chlo·ride/ (ben″zal-ko´ne-um) a quaternary ammonium compound used as a surface disinfectant and detergent, topical antiseptic, and antimicrobial preservative.
benz·al·ko·ni·um chloride (bnzl-kn-m)
n.
A powder prepared in an aqueous solution and used as a fungicide, bactericide, and spermicide.

benzalkonium chloride,
a disinfectant and fungicide prepared in an aqueous solution in various strengths.

benzalkonium chloride
a quaternary ammonium compound used as a surface disinfectant and detergent and as a topical antiseptic and antimicrobial preservative. See also zephiran.

antiseptic 
An agent that kills or prevents the growth of bacteria. This term is generally restricted to agents that are sufficiently non-toxic for superficial application to living tissues. These include the preservatives for eye drops and contact lens solutions. Examples of antiseptics are alcohol, benzalkonium chloride, cetrimide, chlorbutanol, chlorhexidine, hydrogen peroxide, thimerosal (or thiomersalate). Other agents that are too toxic to be applied to living tissues are called disinfectants and are used to sterilize instruments and apparatus. See disinfection; ethylenediamine tetraacetic acid; neutralization; sterilization.


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Another substance that has been implicated in the development of rhinitis medicamentosa is benzalkonium chloride (BAC), an antimicrobial preservative often found in nasal sprays.
Proposed mechanisms for the paradoxical bronchospastic effect of albuterol include bronchospasm secondary to other compounds in the albuterol preparations such as benzalkonium chloride (used as a preservative in nebulizer solutions), (5) chlorofluorocarbons (used as propellants in metered dose inhalers), (5) and oleic acid (used as a dispersant in MDIs), (5) and the presence of (S)-albuterol in racemic preparations of albuterol.
Second, although not proved efficacious against cutaneous chytridiomycosis, the use of benzalkonium chloride, a recognized therapy for infections with non-hyphal fungi, failed to reduce mortality rates.
 
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