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olmesartan medoxomil |
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olmesartan medoxomil, an antihypertensive agent. olmesartan medoxomil Benicar, Olmetec (UK) Pharmacologic class: Angiotensin II type 1-receptor antagonist Therapeutic class: Antihypertensive Pregnancy risk category C (first trimester), D (second and third trimesters) FDA Boxed Warning• When used during second or third trimester of pregnancy, drug may cause fetal harm or death. Discontinue as soon as possible when pregnancy is detected. ActionSelectively blocks binding of angiotensin II to specific tissue receptors in vascular smooth muscle and adrenal gland. This action blocks vasoconstrictive effects of renin-angiotensin system as well as aldosterone release, thereby reducing blood pressure and possibly preventing vascular remodeling related to arteriosclerosis. AvailabilityTablets: 5 mg, 20 mg, 40 mg ⊘Indications and dosages ➣ Hypertension Adults: 20 mg P.O. once daily; may titrate to 40 mg daily after 2 weeks, if needed Dosage adjustment• Volume depletion Contraindications• Hypersensitivity to drug or its components PrecautionsUse cautiously in: Administration• Give with or without food.
Adverse reactionsCNS: fatigue, dizziness, headache, insomnia CV: orthostatic hypotension, chest pain, peripheral edema, syncope, tachycardia EENT: sinusitis, rhinitis, pharyngitis GI: nausea, diarrhea, constipation, abdominal pain, dry mouth GU: hematuria Hematologic: hyperglycemia Musculoskeletal: back pain, arthritis, muscle weakness Respiratory: upper respiratory infection symptoms, bronchitis, cough Skin: dry skin, rash, inflammation, pruritus, alopecia, angioedema Other: dental pain, flulike symptoms InteractionsDrug-diagnostic tests. Triglycerides: increased level Drug-herbs. Ephedra (ma huang): antagonism of antihypertensive effect Patient monitoring• Monitor vital signs and cardiovascular status. Stay alert for orthostatic hypotension, syncope, and peripheral edema. Patient teaching• Tell patient to take at same time each day, with or without food. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Sankyo and Daiichi Pharmaceutical have a broad range of major drug products on the Japanese market, including the antihypertensive Benicar (olmesartan medoxomil) and the synthetic antibacterial agent Cravit (levofloxacin). nbsp;receptor blocker (ARB) olmesartan medoxomil, or Benicar. Principal brands include Lexapro for depression, Namenda for Alzheimer's disease and Benicar for high blood pressure. |
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