Bence Jones proteinuria


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Bence Jones pro·tein·u·ri·a

(bents jōnz),
presence of Bence Jones proteins in the urine, usually indicative of a neoplastic process such as Bence Jones myeloma (multiple myeloma), amyloidosis, or Waldenström macroglobulinemia.

Bence Jones pro·tein·u·ri·a

(bens jōnz prō'tē-nyūr'ē-ă)
Presence of Bence Jones protein in the urine, indicative of multiple myeloma, amyloidosis, or Waldenström macroglobulinemia.

Bence Jones proteinuria

The presence of BENCE JONES PROTEIN in the urine.

proteinuria

an excess of serum proteins in the urine; an important indicator of renal disease. It is a constant finding in glomerulonephritis, renal infarction, amyloidosis and nephrosis, but is also common in congestive heart failure and renal ischemia of all kinds. The significance of proteinuria as an indicator of renal disease is greatly enhanced by the presence of renal casts in the urine.

Bence Jones proteinuria
neonatal proteinuria
occurs transiently during the period of intestinal absorption of proteins, some of which are small enough to pass the glomerular membrane.
References in periodicals archive ?
Nine sera from patients with Bence Jones proteinuria were evaluated separately.
Unless a patient has preexisting renal disease, the presence of significant albuminuria (>600 mg/day) in combination with Bence Jones proteinuria strongly suggests either AL amyloidosis or LCDD (11).
In fact, 16% of patients with likely Bence Jones proteinuria were missed by the F [kappa] and F [lambda] antisera.
Even in this 11% of cases (of intact monoclonal immunoglobulins), an accompanying small amount of Bence Jones proteinuria cannot be excluded because the detection rates with the F [kappa] and F [lambda] reagents were much lower than those with the F+B light chain reagents.
Ratio of urinary free immunoglobulin light chain is to A in the diagnosis of Bence Jones proteinuria.
Although the primary focus of MDI-LabLink is the quantification of glomerular or tubular damage, it suggested immunofixation in most cases of Bence Jones proteinuria (7 of 10 cases of the study group) seen on the gel by routinely calculating the difference between total protein content and the sum of all measured specific proteins (19).
The sensitivity of gold staining in the detection of Bence Jones proteinuria.