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Beckwith's syndrome |
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Beckwith's syndrome
Etymology: John B. Beckwith, American pathologist, b. 1933 a hereditary disorder of unknown cause associated with neonatal hypoglycemia and hyperinsulinism. Clinical manifestations include gigantism, macroglossia, omphalocele or umbilical hernia, visceromegaly, hyperplasia of the kidney and pancreas, and extreme enlargement of the cells of the adrenal cortex. Treatment consists of adequate glucose, diazoxide, and glucocorticoid therapy. Subtotal pancreatectomy is often necessary in cases of beta cell hyperplasia, nesidioblastosis, or beta cell tumor of the pancreas. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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