Becker muscular dystrophy


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Related to Becker muscular dystrophy: distal muscular dystrophy

Beck·er mus·cu·lar dys·tro·phy

, Becker-type tardive muscular dystrophy (bek'ĕr),
a hereditary muscle disorder of late onset, usually in the second or third decade, affecting the proximal muscles with characteristic pseudohypertrophy of the calves; clinical features similar to Duchenne muscular dystrophy but much milder and not a genetic lethal; X-linked recessive inheritance, with both Becker and Duchenne dystrophies caused by mutation in the dystrophin gene on Xp. Compare: Duchenne dystrophy.

Becker muscular dystrophy

(bĕk′ər)
n.
A form of muscular dystrophy that begins in late childhood or adolescence, almost exclusively affects males, and is characterized by progressive weakening of the muscles that is similar to but less severe than in Duchenne muscular dystrophy. It is caused by a recessive genetic mutation on the X chromosome that results in insufficiency or abnormality of the protein dystrophin in muscle cells.

Beck·er mus·cu·lar dys·tro·phy

,Becker-type tardive musculardystrophy (bek'er mŭs'kyū-lăr dis'trŏ-fē, -tīp tahr'div)
A hereditary muscle disorder of late onset, usually in the second or third decade, affecting the proximal muscles with characteristic pseudohypertrophy of the calves; clinical features similar to Duchenne muscular dystrophy but much milder and not a genetic lethal; X-linked recessive inheritance, with both Becker and Duchenne dystrophies caused by mutation in the dystrophin gene on Xp.
Compare: Duchenne dystrophy

Becker muscular dystrophy (BMD)

A type of muscular dystrophy that affects older boys and men, and usually follows a milder course than DMD.
Mentioned in: Muscular Dystrophy

Becker,

Peter Emil, German geneticist, 1908–.
Becker muscular dystrophy - a muscular dystrophy that has many of the clinical features of Duchenne muscular dystrophy. Synonym(s): adult pseudohypertrophic muscular dystrophy; Becker-type tardive muscular dystrophy
Becker-type tardive muscular dystrophy - Synonym(s): Becker muscular dystrophy
References in periodicals archive ?
Frame-shift deletions in patients with Duchenne and Becker muscular dystrophy.
Immunohistochemical staining of Dystrophin on formalin fixed paraffin embedded sections in Duchenne / Becker muscular dystrophy and manifesting carriers of Duchenne muscular dystrophy.
Deletion mutations in the dystrophin gene of Saudi patients with Duchenne and Becker muscular dystrophy.
The report reviews key players involved in the therapeutics development for Becker Muscular Dystrophy and enlists all their major and minor projects
Integrated DNA, cDNA, and protein studies in Becker muscular dystrophy show high exception to the reading frame rule.
Becker muscular dystrophy results from a genetic defect that reduces the amount of a protein called dystrophin in the membrane of muscle cells.
Relatively low proportion of dystrophin gene deletions in Israeli Duchenne and Becker muscular dystrophy patients.
DGGE-based whole gene mutation scanning of the dystrophin gene in Duchenne and Becker muscular dystrophy patients.
15 October 2010 - US biopharmaceutical company PTC Therapeutics Inc said today that final analyses of Phase IIb efficacy data suggest ataluren slowed the loss of walking ability in patients with nonsense mutation dystrophinopathy, a disease continuum comprising Duchenne and Becker muscular dystrophy (nmDBMD).
About 1,800 children and adults in Wales are affected by primary muscle disease, which includes Duchenne and Becker muscular dystrophy.
Landmark breakthroughs by MDA-funded scientists have resulted in the discovery of the cause of Duchenne muscular dystrophy, the most common childhood form of the disorder, and the similar but less severe Becker muscular dystrophy.