Becker muscular dystrophy


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Related to Becker muscular dystrophy: distal muscular dystrophy

Beck·er mus·cu·lar dys·tro·phy

, Becker-type tardive muscular dystrophy (bek'ĕr),
a hereditary muscle disorder of late onset, usually in the second or third decade, affecting the proximal muscles with characteristic pseudohypertrophy of the calves; clinical features similar to Duchenne muscular dystrophy but much milder and not a genetic lethal; X-linked recessive inheritance, with both Becker and Duchenne dystrophies caused by mutation in the dystrophin gene on Xp. Compare: Duchenne dystrophy.

Becker muscular dystrophy

(bĕk′ər)
n.
A form of muscular dystrophy that begins in late childhood or adolescence, almost exclusively affects males, and is characterized by progressive weakening of the muscles that is similar to but less severe than in Duchenne muscular dystrophy. It is caused by a recessive genetic mutation on the X chromosome that results in insufficiency or abnormality of the protein dystrophin in muscle cells.

Beck·er mus·cu·lar dys·tro·phy

,Becker-type tardive musculardystrophy (bek'er mŭs'kyū-lăr dis'trŏ-fē, -tīp tahr'div)
A hereditary muscle disorder of late onset, usually in the second or third decade, affecting the proximal muscles with characteristic pseudohypertrophy of the calves; clinical features similar to Duchenne muscular dystrophy but much milder and not a genetic lethal; X-linked recessive inheritance, with both Becker and Duchenne dystrophies caused by mutation in the dystrophin gene on Xp.
Compare: Duchenne dystrophy

Becker muscular dystrophy (BMD)

A type of muscular dystrophy that affects older boys and men, and usually follows a milder course than DMD.
Mentioned in: Muscular Dystrophy

Becker,

Peter Emil, German geneticist, 1908–.
Becker muscular dystrophy - a muscular dystrophy that has many of the clinical features of Duchenne muscular dystrophy. Synonym(s): adult pseudohypertrophic muscular dystrophy; Becker-type tardive muscular dystrophy
Becker-type tardive muscular dystrophy - Synonym(s): Becker muscular dystrophy
References in periodicals archive ?
Signs and symptoms of Duchenne muscular dystrophy and Becker muscular dystrophy among carriers in the Netherlands: a cohort study.
20, 2014 /PRNewswire-USNewswire/ -- Data published today in the journal Molecular Therapy demonstrates initial clinical proof of principle of a gene therapy to increase muscle strength and function in Becker muscular dystrophy patients.
Antisense oligomers can alter gene expression by snipping out the disease-causing mutation of a gene transcript during the splicing step of gene expression to convert DMD to the much less disabling Becker muscular dystrophy," said Wilton.
About PPMD Parent Project Muscular Dystrophy (PPMD) is a national not-for-profit organization founded in 1994 by parents of children with Duchenne and Becker muscular dystrophy.
Becker muscular dystrophy (BMD) and Limb-Girdle muscular dystrophy (LGMD): Although both BMD and DMD are caused by mutations in the dystrophin gene, BMD is a milder form of dystrophy than DMD.
This is especially exciting for rare disorders like Duchenne and Becker muscular dystrophy, where health data networks may provide a pathway to faster, more effective clinical research to answer questions important to the Duchenne and Becker muscular dystrophy community.
About PPMD Parent Project Muscular Dystrophy is a national not-for-profit organization founded in 1994 by parents of children with Duchenne and Becker muscular dystrophy.
When I was first diagnosed with Becker muscular dystrophy 36 years ago, I'm not sure that anyone would have envisioned I would be a 44-year-old man with a passion for the Mets, Bruce Springsteen and serving as the University Dean for Student Affairs at City University of New York," said Chris Rosa, Ph.
The program is currently in a Phase I/II trial at Nationwide Children's Hospital in adult patients with Becker muscular dystrophy and inclusion body myositis, a trial funded by the foundation Parent Project Muscular Dystrophy.
DMD patients often die at a much younger age than patients with Becker muscular dystrophy due to heart failure.