Bazin disease


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er·y·the·ma in·du·ra·tum

recurrent hard subcutaneous nodules that frequently break down and form necrotic ulcers, usually on the calves and less frequently on the thighs or arms of middle-aged women; they are associated with erythrocyanotic changes in cold weather; although microscopically granulomatous and necrotizing, the lesions are sterile; but tuberculin skin tests are usually positive and polymerase chain reaction amplification is frequently positive for Mycobacterium tuberculosis complex DNA.

er·y·the·ma in·du·ra·tum

(er'i-thē'mă in-dū-rā'tŭm)
Recurrent hard subcutaneous nodules that frequently break down and form necrotic ulcers, usually on the calves and less frequently on the thighs or arms of middle-aged women; probably a form of nodular vasculitis.
Synonym(s): Bazin disease.

Bazin disease

(ba-zin')
[Antoine P. E. Bazin, Fr. dermatologist, 1807–1878]
A chronic skin disease occurring in young adult females; characterized by hard cutaneous nodules that break down to form necrotic ulcers that leave atrophic scars. The disease is almost invariably preceded by tuberculosis, but the etiological relationship to that disease is debated.
Synonym: erythema induratum

Bazin,

Antoine Pierre Ernest, French dermatologist, 1807-1878.
Bazin disease - recurrent, hard, subcutaneous nodules that frequently break down and form necrotic ulcers, usually on the calves; lesions are sterile and probably a form of nodular vasculitis. Synonym(s): erythema induratum; nodular tuberculid