phenazopyridine hydrochloride

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Related to Baridium: Prodium, Urogesic

phenazopyridine hydrochloride

AZO-Gesic, Azo-Standard, Baridium, Phenazo (CA), Prodium, Pyridium, ReAzo, UTI Relief

Pharmacologic class: Nonopioid analgesic

Therapeutic class: Urinary analgesic

Pregnancy risk category B


Unknown. Thought to act locally on urinary tract mucosa to produce analgesic or anesthetic effects, relieving urinary burning, urgency, and frequency.


Tablets: 95 mg, 97.2 mg, 100 mg, 200 mg

Indications and dosages

Pain caused by lower urinary tract irritation

Adults: 200 mg P.O. t.i.d.

Children: 12 mg/kg P.O. daily in three divided doses


• Hypersensitivity to drug
• Renal insufficiency


Use cautiously in:
• hepatitis
• pregnant or breastfeeding patients
• children younger than age 12.


• Give with or after meals.
• Discontinue after 2 days, as prescribed, when administering with antibiotics.

Adverse reactions

CNS: headache

EENT: contact lens staining

GI: GI disturbances

GU: bright orange urine, renal toxicity

Hepatic: hepatotoxicity

Hematologic: hemolytic anemia,


Skin: rash, pruritus

Other: anaphylactoid-like reaction


Drug-diagnostic tests.Bilirubin, glucose, ketones, protein, steroids: interference with urine tests based on spectrophotometry or color reactions

Patient monitoring

• Monitor patient for symptomatic improvement of urinary tract infection (UTI).
• Assess follow-up urine culture after antibiotic therapy ends.

Monitor for yellowing of skin or sclera. This change may indicate drug accumulation caused by impaired renal excretion, warranting drug withdrawal.

Patient teaching

• Explain drug therapy and measures to help prevent UTI recurrence.
• Tell patient drug may discolor urine and tears and may stain clothing and contact lenses.

Advise patient to contact pre-scriber promptly if symptoms don't improve or if skin or eyes become yellow.
• As appropriate, review all other significant and life-threatening adverse reactions and interactions, especially those related to the tests mentioned above.

phen·az·o·pyr·i·dine hy·dro·chlor·ide

(fen'ā-zō-pēr'i-dēn hī'drō-klō'īd),
An orally administered urinary tract analgesic.

phenazopyridine hydrochloride

An oral analgesic used to treat urinary tract pain and urgency.

phenazopyridine hydrochloride

a urinary tract analgesic.
indications It is prescribed to reduce the pain of cystitis or other urinary tract infections or to relieve the pain following clinical procedures of the urinary tract.
contraindications Renal or hepatic insufficiency or known hypersensitivity to this drug prohibits its use.
adverse effects Among the more serious adverse effects are headache and GI disturbances.