bare lymphocyte syndrome

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bare lymphocyte syndrome (bâr)

The absence of human leukocyte antigens on peripheral mononuclear cells, which may result in immunodeficiency.

bare lymphocyte syndrome,

an immune deficiency condition caused by defective beta-2 microglobulin, one of the major histocompatibility antigens on cell surfaces. It is inherited as an autosomal-recessive trait. The deficiency causes a severe combined immunodeficiency resulting from the lack of antigen presentation by type I and/or type II major histocompatibility complex.

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