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Balloon Cell

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Balloon Cell
Cytology A general term for markedly enlarged cells seen on cervical smears which may be mono-, bi- or multinucleated; the nuclei may be dyskeratotic
Pathology A nonspecific term for a cell with abundant clear cytoplasm, which may be benign or malignant and may be of any embryologic origin and may contain any histologically clear material
Examples Carcinoid cells, ependymal cells (myxopapillary ependymoma, hepatocytes), ballooning degeneration, histiocytes storing glycosaminoglycans and mucopoly-saccharides, neurons (Farber’s disease, lipogranulomatosis, mannosidosis) and pigmented cells either benign (balloon cell nevus) or malignant (balloon cell melanoma)
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Balloon cells develop in any damaged mucosa, but in the absence of other more characteristic features of GERD, they may be the only clue that a chemical injury has occurred.
Update on esophagitis: controversial and underdiagnosed causes by Noffsinger, Amy E. / Archives of Pathology & Laboratory Medicine
 
 
 
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