bacterial artificial chromosome


Also found in: Dictionary, Acronyms, Wikipedia.
Related to bacterial artificial chromosome: Yeast artificial chromosome

bacterial artificial chromosome

n. Abbr. BAC
A large DNA sequence that is artificially inserted into a bacterial genome for replication or expression.

bacterial artificial chromosome (BAC)

CLONING VECTOR based on the F PLASMID of ESCHERICHIA COLI, with the capacity to accept DNA inserts generally 100–300kb in size. Often used in the CLONE CONTIG SEQUENCING METHOD to obtain sequence CONTIGS in a genome sequencing project. See HUMAN GENOME PROJECT.
References in periodicals archive ?
Construction and characterization of a bacterial artificial chromosome (BAC) library for the A genome of wheat.
Construction and characterization of a half million clones: Bacterial Artificial Chromosome (BAC) library of durum wheat.
Bacterial artificial chromosome libraries have also been used to develop physical maps for genomic regions containing resistance gene analog sequences (Marek and Shoemaker, 1997).
We have now launched a test based on our Bacterial Artificial Chromosome Platform (see http://www.
With the Spectral Genomics Array CGH Platform, PerkinElmer is now the only company to offer a Bacterial Artificial Chromosome (BAC) based integrated solution consisting of the SpectralChip 2600 array, the Constitutional Chip 3.
A Bacterial Artificial Chromosome array is a highly efficient and accurate means of detecting genetic abnormalities responsible for a variety of human maladies, such as Down Syndrome, autism, and cancer.
In October, Solexa announced that Company scientists had sequenced a human Bacterial Artificial Chromosome (BAC) on an early laboratory prototype instrument.
Further, last month we announced the successful resequencing of a human bacterial artificial chromosome, which demonstrates that our reversible-terminator chemistry and Clonal Single-Molecule Array(TM) technology can be applied to resequence human DNA.
Nasdaq:SLXA) today announced that its scientists have sequenced a human bacterial artificial chromosome (BAC), an important milestone demonstrating that Solexa's reversible-terminator chemistry and Clonal Single-Molecule Array(TM) technology can be applied to resequence human DNA.
The technique, developed by a team at the University of California, San Diego, uses bacterial artificial chromosomes (BACs) to insert defective copies of genes into stem cells.
We have also developed the capabilities of producing arrays that utilize bacterial artificial chromosomes on our arrays, also enabling genetic analysis.