BRWD1

BRWD1

A gene on chromosome 21q22.2 that encodes a member of the WD-repeat protein family, which are involved in various cellular processes, including cell cycle progression, signal transduction, apoptosis and gene regulation. BRWD1 is located within the Down syndrome region-2 on chromosome 21; it may be a transcriptional activator, and may be involved in chromatin remodelling.
References in periodicals archive ?
Moreover, RUNX1 registered mid values of over expression in CN, Pu and GP; BRWD1, CLIC6, ETS2, and SH3BGR had low levels of expression.
BRWD1 and DYRK1A registered low levels of expression in the CA 4 (-1.