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Abbreviation for Bruton tyrosine kinase.


A gene on chromosome Xq21.33-q22 that encodes a protein which plays a central role in B-cell development, differentiation and signalling. Binding of antigens to the B-cell antigen receptor (BCR) triggers signalling that leads to B-cell activation. 

Molecular pathology
Defects of BTK cause X-linked agammaglobulinaemia (OMIM:300755), as well as X-linked hypogammaglobulinaemia and isolated growth hormone deficiency (OMIM:307200).

Bruton's agammaglobulinemia tyrosine kinase (Btk)

An enzyme vital for the maturation of B cells.
References in periodicals archive ?
Consequently, those who are in a better position to achieve reasonable career success as auditors of BPK would be single middle-aged women or those married women who have been working for more than 20 years whereby their children would no longer require close supervision and that their husbands would have already achieved financial stability.
Agama dan Kerukunan [Religion and Harmony] (Jakarta: BPK Gunung Mulia, 2001), 222-238.
As an example, consider a tree with values for DBH and AGE very near the means, that is a tree with 20-inch DBH and 150 years old, and BPK = 0.
Acxiom's recent acquisition of the Claritas Europe companies (including Altwood Systems and BPK of The Netherlands) serves to add yet more weight to the new partnership.
Table--1 Production of Plywood 2005-2009 (Cubic meters) Year 2005 2006 2007 2008 2009 Volume 4,533,749 3,811,794 3,454,350 3,353,479 3,004,950 Growth (%) -- -15,90 -9,38 -2,92 -10,39 Sources : Directorate of BPPHH, BPK directorate general, Forestry Ministry Table--2 Production of plywood by provinces, 2005-2009 (Cubic meters) No.
Claritas services operations include Altwood Systems in Kent, England; and BPK Group in Almere and Nieuwegein, the Netherlands.
BPK has reported that it has found 3,266 "wild" bank accounts valued at Rp18.
The contractor is responsible to the National Bank of Hungary (hereinafter referred to as the contracting entity) which parts of the system ISTAT1 CASIR (EPSI, FISIM, FMR, GESMES, MON, PSZLA, PSZLA VMR and developed in the future CASIR new systems) and CSDB, andSTART 2, EBEAD KTM BPK and IT applications to support software development and operational support.
The BPK had submitted its report to the House of Representatives (DPR), which later passed it onto the Attorney General.
The tug is powered by Rolls-Royce BPK 155 US propulsion system, FPP into nozzles, with Caterpillar C32 twin engines rated power 2x746 kW at 1800 r / min.
The MoU is part of BPK s effort to reduce the chances for corrupt practices.