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Abbreviation for Bruton tyrosine kinase.


A gene on chromosome Xq21.33-q22 that encodes a protein which plays a central role in B-cell development, differentiation and signalling. Binding of antigens to the B-cell antigen receptor (BCR) triggers signalling that leads to B-cell activation. 

Molecular pathology
Defects of BTK cause X-linked agammaglobulinaemia (OMIM:300755), as well as X-linked hypogammaglobulinaemia and isolated growth hormone deficiency (OMIM:307200).

Bruton's agammaglobulinemia tyrosine kinase (Btk)

An enzyme vital for the maturation of B cells.
References in periodicals archive ?
Data from BPK said that there are four KAPs winning the tender to audit the nine ministries and government agencies.
Hermes BPK Partnersa[euro](tm) chief executive officer and founding partner, Matteo Dante Perruccio, said that hedge funds are increasingly being seen as an intelligent and efficient way of accessing the opportunities in Asia while enhancing the risk return profile.
We are doing it as recommended by the BPK," Herry said, but declined to offer information about the recovered assets.
In a similar vein, a woman working as a (public sector) auditor in BPK also noted that role conflict might lessen as family responsibilities eased:
69) The BPK does not elaborate which "national institutions" received money from the Sleman APBD but judging by trends in the other districts it is likely the police and the military absorbed some of these funds.
Direct economic impacts (in Rp million; assessed in May 2007 by the audit board of the republic of Indonesia [BPK], Source: BPK, 2007, p.
Variables included in the initial all subsets run were: AGE, AREA_YR, BARK_TYP, BPK, DBH, GROWTH, GRS_VOL, HT, and SWEEP (Table 1).
Simatupang, 'Sebagai penutup: Sepuluh dalil', in Iman Kristen dan Pancasila (Jakarta: BPK Gunung Mulia, 1985), p.
Claritas Europe service operations include Altwood Systems (Kent, UK) and BPK Group (Almere, the Neth.