BMPR1A


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BMPR1A

A gene on chromosome 10q22.3 that encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases, which binds and activates SMAD transcription regulators. BMPR1A is a receptor for BMP-2 and BMP-4.
 
Molecular pathology
BMPR1A mutations cause juvenile polyposis syndrome, hereditary mixed polyposis syndrome 2, and may cause Cowden disease.
References in periodicals archive ?
Genes Tested AtP ALK APC ATM BAP1 BRCA2 BRIP1 BUB1B CDC73 CDH1 CEP57 CHEK2 CYLD DDB2 DICER1 ERCC3 ERCC4 ERCC5 EXT1 EXT2 FANCD2 FANCE FANCF FANCG FANCI GATA2 GPC3 HNF1A HOXB13 HRAS MLH1 MHS2 MSH6 MUTYH NBN PHOX2B PMS1 PMS2 PPM1D PRF1 RAD51D RBI RECQL4 RET RHBDF2 SDHC SDHD SLX4 SMAD4 SMARCA4 TP53 TSC1 TSC2 VHL WT1 BARD1 BLM BMPR1A BRCA1 CDK4 CDKN1C CDKN2A CEBPA DI53L2 EGFR EPCAM ERCC2 EZH2 FANCA FANCB FANCC FANCL FANCM FH FLCN KIT MAX MEN1 MET NF1 NF2 NSD1 PALB2 PRKAR1A PTCH1 PTEN RAD51C RUN XI SBDS SDHAF2 SDHB SMARCB1 STK11 5UFU TMEM127 WRN XPA XPC This chart shows all 98 cancer susceptible genes included in this new test.
5), antigen CD56 (CD56), Cathepsin D, RET, BMPR1A, and bcl-2 immunohistochemistry can be used.
In addition, apigenin treatment has an influence on the genes involved in metabolism (SLC27A3, P4HB and GLDC), DNA-dependent regulation of transcription (OVOL1 and OTP), cell signal transduction (ECT2, MAPK1IP1L, BMPR1A and AMFR), cell motility (AMFR), inflammatory response (CCR2) and other biological processes (HIP1R, ZDHHC2, NUP35 and SLC10A2).