BMP8B


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BMP8B

A gene on chromosome 1p35-p32 that encodes bone morphogenetic protein-8b, which may play a role in early development and bone induction.
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2E-11 factor receptor activity BMP8B, CSF1, FCFR1, BMPR2, 1GF2R, PDCFB, TGFBR2, NRP1, CCR2 Biosynthetic process CEL, COL11A2, ACPP, MMP14, 1.
The research, led by scientists at the University of Cambridge Metabolic Research Laboratories at the Institute of Metabolic Science, discovered that the protein BMP8B acts on a specific metabolic system (which operates in the brain and the tissues) to regulate brown fat, making it a potential therapeutic target.
However, BMP8B seems to be very specific for regulating the heat producing activity of brown fat, making it a more ideal mechanism for new therapies.
The experiments showed that when mice lacked the protein BMP8B they found it more difficult to maintain their normal body temperature.
The research, which was conducted in mice and led by scientists at the University of Cambridge Metabolic Research Laboratories at the Institute of Metabolic Science, discovered that the protein BMP8B acts on a specific metabolic system (which operates in the brain and the tissues) to regulate brown fat, making it a potential therapeutic target.
However, BMP8B seems to be very specific for regulating the heat producing activity of brown fat, making it a more ideal mechanism for new therapies," said Dr Andrew Whittle, one of the authors of the paper from the Institute of Metabolic Science.
Additionally, when the researchers treated brown fat cells with BMP8B they responded more strongly to activation by the nervous system.