BMP15

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BMP15

A gene on chromosome Xp11.2 that encodes bone morphogenetic protein 15, which is thought to play a role in oocyte and follicular development.
References in periodicals archive ?
These results showed that BMP-15 gene is a genetic marker and closely linkage to the litter size trait and consequently can be used as a marker-assisted selection (MAS) for high litter size productivity in sheep.
In mammals BMP-15 is the product of an X-linked gene expressed in oocytes (Dube et al.
Are BMP-15 and GDF-9 primary determinants of ovulation quota in mammals?
Unfortunately, in our study, no indication was found for under-expression of BMP-15 or GDF-9, since cumulus expansion is necessary for a proper oocyte development (Zhang et al.
Members of each subgroup (BMP-2, BMP-4, BMP-6, BMP-7, BMP-15, and growth differentiation factor-9(GDF-9)) have been shown to affect ovarian folliculogenesis, follicular growth and differentiation, cumulus expansion, ovulation and luteinization (Knight and Glister, 2006).
In the TGF-[beta] subfamily, GDF-9 and BMP-15 are essential for ovarian follicular growth (Juengel et al.