LAMA3

(redirected from BM600)

LAMA3

A gene on chromosome 18q11.2 that encodes laminin alpha 3, an extracellular matrix subunit of laminin 5, which is a complex glycoprotein composed of three subunits (alpha, beta and gamma) involved in cell adhesion, signal transduction and keratinocyte differentiation.

Molecular pathology
LAMA3 mutations are associated with junctional epidermolysis bullosa (Herlitz type).