BK virus


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Related to BK virus: Polyomavirus

BK vi·rus

a human polyomavirus, in the family Papovaviridae, of worldwide distribution, that produces kidney infections that are usually subclinical in immunocompetent people.
[initials of patient from whom first isolated]

BK virus

A small human polyomavirus which, like the JC virus, can transform infected cells in culture; up to 80% of the general population (US) have been exposed to it.

Clinical findings
Primary BKV infection is usually subclinical, most common in early childhood, persists in renal epithelium and may become reactivated, causing severe tubulointerstitial nephritis, and cystitis in BM transplant recipients or in immunocompromised patients—e.g., those with hyper-IgM immunodeficiency syndrome; BKV may cause encephalitis.
 
Diagnosis
Serology—IgM, IgG antibodies; PCR; T2-weighted MRI.

BK virus

Infectious disease A small human polyomavirus which, like the JC virus, can transform infected cells in culture; 1º BKV infection is usually subclinical, is most common in early childhood, persists in renal epithelium and may be reactivated, causing severe tubulointerstitial nephritis, and cystitis in BM transplant recipients, or in the immunocompromised Pts–eg, those with hyper-IgM immunodeficiency syndrome; BKV may cause encephalitis Diagnosis Serology–IgM, IgG antibodies; PCR, T2-weighted MRI. See Polyomavirus. Cf JC virus.
References in periodicals archive ?
Incidence of BK virus and JC virus viruria in human immunodeficiency virus-infected and uninfected subjects.
Preemptive retransplantation for BK virus nephropathy: successful outcome despite active viremia.
BK virus infection in hematopoietic stem cell transplant recipients: frequency, risk factors, and association with postengraftment hemorrhagic cystitis.
Persistence of DNA sequences of BK virus and JC virus in normal human tissues and in diseased tissues.
JC and BK virus sequences are not detectable in leukaemic samples from children with common acute lymphoblastic leukaemia.
Two patients with no detectable BK virus had rising creatinine levels and neurologic symptoms that suggest JC virus infection could have a different course from BK virus infection, Dr.
BK virus has tropism for human salivary gland cells in vitro: implications for transmission.
Prospective monitoring of cytomegalovirus, Epstein-Barr virus, BK virus, and JC virus infections on belatacept therapy after a kidney transplant," Experimental and Clinical Transplantation, vol.
The BK virus and the JC virus are the polyomaviruses that have been found to cause infections in humans and can contribute to the development of polyomavirus infection in transplant recipients (Costa & Cavallo, 2012).
Nowadays, there is no effective treatment for the BK virus infection.