BIRC2

BIRC2

A gene on chromosome 11q22 that encodes a protein which inhibits apoptosis by binding to tumour necrosis factor-receptor-associated factors TRAF1 and TRAF2, interfering with activation of ICE-like proteases.
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53-57) For example, novel candidate oncogenes include SMURF1 on 7q21, FGFR1 on 8p12, BIRC2 and BIRC3 on 11q22, and PAK4 on 19q13, whereas novel candidate tumor suppressor genes include TUSC3 on 8p22 and FEZ1 on 8p23.