BDNF


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BDNF

A gene on chromosome 11p13 that encodes brain-derived neurotrophic factor, a nerve growth factor that promotes the survival, migration and differentiation of neuronal precursors in the peripheral and central nervous system, and supports survival of primary sensory neurones originating from the neural crest and ectodermal placodes.
References in periodicals archive ?
Protein levels of BDNF and TrkB in the 100 mg/kg GLe-treated group were not significantly different from those in the vehicle-treated group [Figure 4].
Therefore, because both BDNF and the HPA axis appear to modulate dopaminergic activity in response to nicotine exposure, this study simultaneously evaluated central (BDNF) and peripheral (cortisol) components related to nicotine consumption by smokers.
And ultimately, rebuilding BDNF levels can recreate brain plasticity to help patients form new response patterns.
It is likely that at least some of the significant improvements in both HPA axis functioning as exemplified by the CAR as well as neuroimmunologic functioning as exemplified by increases in BDNF levels and alterations in cytokines were due to the intensive meditation practice involved in this retreat," says corresponding author Dr Baruch Rael Cahn (University of Southern California, USA).
Immediately after completion of the final blood sampling, the rats were sacrificed, and their hippocampus was removed to measure messenger RNA (mRNA) expression of Bax, Bcl-2, and BDNF.
KEYWORDS: Physical activity, Morphine, Abstinence syndrome, Psychological dependency, BDNF, TrkB Hippocampus, Rat.
Therefore, the objective of this study was to investigate the serum levels of BDNF, pro-BDNF, NGF, GDNF, neurotrophin (NT)-3, and NT-4/5 in TR patients, before and after treatment, comparing with control subjects.
Results: RSV (120 mg/kg BW/day) caused a statistically significant increase in the expression levels of BDNF exons III, IV and IX, but not the exon I in the hippocampi of adult rats (P[less than or equal to]0.
Taken together, these findings indicate that a specific group of POA cells that express both PACAP and BDNF are dedicated to detecting warm temperatures, that they do so by monitoring signals from sensors in the skin, and that they prompt an array of both physiological and behavioral strategies to return the body to a cooler temperature.
2015) [Anxiety and polymorphism Val66Met of BDNF gene predictors of depression severity in ischemic heart disease].