BCNU


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carmustine

 [kahr-mus´tēn]
a cytotoxic alkylating agent of the nitrosourea group, used as an antineoplastic agent, primarily against brain tumors, multiple myeloma, colorectal carcinoma, Hodgkin's disease, and non-Hodgkin's lymphomas. Called also BCNU.

car·mus·tine

(kar-mŭs'tēn),
An antineoplastic agent.
Synonym(s): BCNU

BCNU

carmustine.

BCNU

BCNU

A chemotherapeutic related to lomustine (CCNU) and semustine, which partially overlaps the activity/toxicity of alkylating agents.
 
Indications
Hodgkin lymphoma, non-Hodgkin lymphoma, melanoma, myeloma, brain tumours, gastrointestinal carcinomas; BCNU crosses the blood-brain barrier and may be used for meningeal leukaemia and brain tumours.
 
Side effects
Nausea, vomiting, decreased platelets, reduced WBCs, secondary leukaemia, pulmonary fibrosis, renal failure.

BCNU

Bis-chlorethylnitrosourea, carmustine A chemotherapeutic related to lomustine–CCNU and semustine, which partially overlaps the activity/toxicity of alkylating agents Indications Hodgkin's disease, possibly NHL, melanoma, myeloma, brain tumors, GI carcinomas; BCNU crosses the blood-brain barrier and may be used for meningeal leukemia and brain tumors Side effects N&V, ↓ platelets, ↓ WBCs, 2º leukemia, pulmonary fibrosis, renal failure

BCNU

References in periodicals archive ?
The purpose is to train up members to eventually become industrial staff or Labour relations officers (LROs) with the BCNU," she said.
Superiority of post-radiotherapy adjuvant chemotherapy with CCNU, procarbazine, and vincristine (PCV) over BCNU for anaplastic gliomas: NCOG 6G61 final report.
U@ - BCNU - LOL: Learn their language to boldly lead Gen X, Y & the Boomers" will address how to utilize the strengths of different personalities, generations and backgrounds.
As a Gliadel Wafer dissolves, BCNU is delivered directly to the site once occupied by the tumor.
A GLIADEL(R) Wafer delivers BCNU (known as carmustine), a commonly used chemotherapeutic anti-tumor agent for GBM, directly to the brain tumor resection cavity.
A Gliadel Wafer delivers BCNU (known as carmustine), a commonly used chemotherapeutic anti-tumor agent for GBM, directly to the brain tumor resection cavity.
The effect was found to be more significant than that of BCNU (which is clinically used for this indication) or of Gleevec(R), another approved anti-cancer drug.
As a Gliadel Wafer dissolves, BCNU is delivered directly to the site once occupied by the tumor, providing site-specific chemotherapy to target any remaining tumor cells.
Certain side effects reported with intravenous delivery of BCNU have not been seen after implantation of Gliadel Wafer.
A GLIADEL(R) Wafer delivers BCNU (or carmustine), a commonly used chemotherapeutic anti-tumor agent for GBM, directly to the brain tumor resection cavity.