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BCL2

   Also found in: Acronyms, Encyclopedia, Wikipedia 0.04 sec.
BCL2 (bs-l-t)
n.
A gene associated with non-Hodgkin's lymphoma that normally helps regulate the life span of a white blood cell but when mutated prevents such cells from dying, allowing possible further mutations and the development of cancer.


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2] also induces the apoptotic regulators BCL2 and BAG1 in cultured breast cancer cells (Perillo et al.
Phenotypic anchoring of gene expression changes during ... by Orphanides, George / Environmental Health Perspectives
The genes most predictive of overall survival in DLBCL were LMO2, BCL6, FN1, CCND2, SCYA3 and BCL2.
Stanford University and Applied Biosystems Identify Gene Expression ... by Business Wire
The t(14;18)(q32;q21) translocation results in the juxtaposition of the BCL2 gene on chromosome 18q21 with the immunoglobulin heavy chain (IGH) gene on chromosome 14q32, causing overexpression of BCL2, which maintains the neoplastic proliferation of B-cells.
Cancer Genetics Awarded Phase II SBIR to Develop Novel Lymphoma Probes by Business Wire
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