BCHE


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BCHE

A gene on chromosome 3q26.1-2 that encodes butyrylcholinesterase, which has a broad substrate spectrum. It contributes to inactivation of the neurotransmitter acetylcholine and can degrade neurotoxic organophosphate esters.
 
Molecular pathology
Mutant alleles at BCHE are responsible for suxamethonium sensitivity.
References in periodicals archive ?
russeliana growing in Turkey were demonstrated to exert AChE inhibitory activity using autobiographic thin layer chromatographic (TLC) tests and, as compared to the extracts in different polarity, the chloroform extracts were concluded to have a higher inhibiting property, which is compliant with our data on BChE (Table-1).
Comunmente la funcion muscular retorna a la normalidad cerca de 10 minutos despues de la interrupcion del medicamento, pero en algunas ocasiones puede existir un bloqueo extendido por variantes de la BChE o por deficiencia en la cantidad de la enzima lo que enlentece el metabolismo de medicamentos con colina o de sustancias quimicas como la succinilcolina y los organofosforados (4, 7).
Se determinaron los niveles de BChE plasmatica utilizando el kit Colinesterasa (GT Lab[R]), metodo cinetico por espectrofotometria a 405 nm, pH 7.
In human lung adenocarcinoma cell line OM, at least four genes ( MME , SI , BCHE , and KNG ) were involved in carcinogenesis.
La deteccion analitica de plaguicidas es un recurso mas costoso que la medicion de BChE.
2013), however these isolated alkaloids were more BChE selective.
In sublethal toxicity, the AChE and BChE activities in blood were significantly reduced after two months of exposure to parathion and carbosulfan (Tables I, II).
The finding that BCHE gene variant predicts the extent of plaque deposit in PET scans among people at risk for Alzheimer's disease is likely to reinvigorate research into drugs that could modify the disease by affecting the BCHE enzyme or its metabolic pathway," he said.
BChE is the product of the BCHE (butyrylcholinesterase) gene on chromosome 3 region 3q26.