BAG4

BAG4

A gene on chromosome 8p11.23 that encodes BCL2-associated athanogene 4, a ubiquitous protein that inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release and prevents TNFRSF1A signalling.
References in periodicals archive ?
They found that at least four genes, called TOMM7, HSPAI1L, BAG4 and SIAH3, may act as helpers.
Turning off some genes, such as TOMM7 and HSPAI1L, inhibited parkin tagging whereas switching off other genes, including BAG4 and SIAH3, enhanced tagging.