BACH2

BACH2

A gene on chromosome 6q15 that encodes a transcription factor which binds to Maf recognition elements (MARE), playing important key roles in co-ordinating transcription activation and repression by MAFK.
References in periodicals archive ?
The 20 most up- and down-regulated genes include significant changes in expression of genes related to apoptosis (FDRX) B-cell functions (FCRLA, IGHM, PAX 5, BACH2, MS4A1, and POU2AF1), inflammation (ITLN1, CCR7), hemoglobin synthesis (XK and RHD), and induced by oxidative stress (SESN3).
The CNC subfamily also includes NRF1 (NFE2L1/LCRF1/TCF11), NRF3 (NFE2L3), and the nuclear factor-erythroid 2 p45 subunit, as well as more distantly related factors such as BTB and CNC homology 1 (BACH1) and BACH2 protein.