GRB7

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GRB7

A gene on chromosome 17q12 that encodes an adapter protein which interacts with the cytoplasmic domain of numerous downstream protein kinases (e.g., STAT3, AKT1, MAPK1 and/or MAPK3), activating them. GRB7 promotes activation of HRAS; it plays a role in signal transduction in response to EGF and in regulating cell proliferation and cell migration. It also plays a role in the assembly and stability of RNA stress granules, binding target mRNA molecules and repressing their translation when not phosphorylated. Phosphorylation impairs RNA binding and promotes stress granule disassembly during recovery from cellular stress.
References in periodicals archive ?
Family flowers only please, donations if so desired to the Alzheimer's Society may be sent to Thomas Brothers, The Funeral Directors, 100 Alcester Road Wythall B47 5HA 01564 822001 Thank you.
On routine missions or special exercises, SAC regularly flew its B47 and B52 bombers over Canada.
Adjustments in lines A5, A13, B12, B47, and B82 reflect CENSUS's
Transportation is in abundance with the Ralph Avenue stop of the C train 3 blocks away and the B47 bus line on the block.
Four-cylinder units will also be offered and will include the new BMW B47 diesel engine, available in the 118d, 120d and 125d.
According to the carrier, the exclusive agreement covers aspirators on Boeing's B737, B47, B767 and B777 airplanes, and the work will be performed at the UTC Aerospace Systems MRO facility in Singapore.
No registro Cidade de origem Tipo do plantel B1 Passo Fundo--RS Frango de corte B2 Montenegro--RS Frango de corte B3 Salvador do Sul--RS Matrizeses B4 Nova Bassano- RS Matrizes B5 Estacao--RS Matrizes B6 Caxias do Sul--RS Matrizes B7 Coqueiros do Sul--RS Matrizes B8 Mormaco--RS Matrizes B9 Nova Bassano Matrizes B10 Salvador do Sul Matrizes B11 Estacao Matrizes B12 Nova Bassano Matrizes B14 Nova Bassano Matrizes B15 Vacaria Avos B16 Vacaria Avos B17 Caxias do sul Matrizes B18 Ipe--RS Avos B19 Ipe Avos B20 Nova Bassano Matrizes B22 ate Montenegro Frango de corte B47 (26 lotes) B48 Dourados--MS Matrizes B49 Dourados--MS Matrizes B50 Laguna Carapa--MS Matrizes No registro Idade na Idade na Semanas apos coleta (sem.
THE Becketts Farm, B47 6AJ A435 to Tel: WOLVES (4-4-2): Ikeme; Foley (Davis,75), Johnson, Berra, Ward; Forde (Peszko,67), O'Hara, Henry, Sako; Doyle (Cassidy,68), Ebanks-Blake.
21) Parte dentro de la cual, los fragmentos 112-125, esto es, en la edicion DK: B115, B47, B46, B67a, A16, B126a, B127, B132, B133, B134, B135, B130 y B138, son considerados dubia et spuria.
But since B47 is spurious (18), it can yield no reliable information concerning Empedocles' understanding of the word (19).
At booth B47, hall 16, the recoSTAR basic will be on show, which is generally used for processing hygroscopic, wet and/or pre-ground materials, but also production waste.