LAMC2

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LAMC2

A gene on chromosome 1q25-q31 that encodes laminin gamma 2, an extracellular matrix protein that with alpha 3 and beta 3 chains constitutes laminin 5, an integral part of the anchoring filaments that connect epithelial cells to the underlying basement membrane.

Molecular pathology
LAMC2 mutations cause junctional epidermolysis bullosa Herlitz type.