ARID1A

(redirected from B120)

ARID1A

A gene on chromosome 1p36.1-p35 that encodes AT-rich interactive domain-containing protein 1, which is highly expressed in the spleen, thymus, prostate, testes, ovaries, small intestine, colon and peripheral leukocytes. ARID1A is involved in transcriptional activation and repression of select genes by chromatin remodelling (by altering DNA-nucleosome topology). It is also involved in vitamin D-coupled transcription regulation by associating with the WINAC complex, a chromatin-remodelling complex recruited by vitamin D receptor.

ARID1A belongs to the neural progenitors-specific chromatin remodelling (npBAF) and the neuron-specific chromatin remodelling (nBAF) complexes, which are involved in switching developing neurons from stem/progenitors to post-mitotic chromatin remodelling as they exit the cell cycle and become committed to their adult state.

Molecular pathology
Defects in ARID1A cause mental retardation autosomal dominant type 14.
References in periodicals archive ?
CIRCUS ACTS THERE will be stories and faces from the circus during an event which will be using non-toxic face paints at Small Heath Library, Muntz Street B120 9RX from 10.
45 MPa [degrees]C IS075/Bf 136 Vicat B120 [degrees]C IS0306 142 Rheological MVR ** cc/10min IS01133 12 Impact Notched Izod kJ/[m.
There are five key technology solutions that make up the product suite, including the iAN8K(TM) B1000 Multimedia Network Edge, BBS 4000 Optical Line Terminal (OLT), iAN8K(TM) B110 IPDSLAM, iAN8K(TM) B120 ADSL2+ and VoIP Combo and BBS 1000+ OLT.
The movie features the Cadillac Cien concept car and Confederate's Wraith B120.
He has served in a wide variety of Naval Reserve billets including six command tours as Commanding Officer of Advanced Supply Base 420, Naval Air Pacific Supply 187, Navy Material Transportation Detachment 520, Defense Contract Management District B 1020, Defense Distribution Depot Oakland Headquarters B320, and Defense Distribution Region West Headquarters B120.
Significant contribution to the achievement of one year without a lost-time accident on the Cox B120 extension project at the Novartis Pharmaceutical manufacturing facility in Grimsby.
10th Street, Suite B120, Indianapolis, IN 46202), iSALUS Healthcare is now located in close proximity to the Indiana University School of Medicine as well as several major hospitals.
Her recent Reserve assignments include Commanding Officer, AIRPAC Supply 0189 and Executive Officer, NR Defense Distribution Center Detachment B120.
FreshBattery also offers replacement batteries for the Dell Inspiron 1300, 6400, B120, B130, E1501, E1505 and Latitude 120L and 131L series.
With a new home, a growing workforce, and the classic motorcycle collection inside the Barber museum to provide inspiration for future designs, Confederate is looking boldly ahead with the production of its first F131 Hellcat and B120 Wraith models.