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B cell |
Also found in: Encyclopedia, Wikipedia, Hutchinson | 0.02 sec. |
B cell (B lymphocyte) A type of white blood cell derived from bone marrow. B cells are sometimes called B lymphocytes. They secrete antibody and have a number of other complex functions within the human immune system. Mentioned in: AIDS Tests, Severe Combined Immunodeficiency, Waldenström's Macroglobulinemia, X-Linked Agammaglobulinemia B cell, a type of lymphocyte that originates in the bone marrow and produces antibodies. A precursor of the plasma cell, it is one of the two lymphocytes that play a major role in the body's immune response. Also called B lymphocyte. Compare T cell. See also plasma cell. B cell see B lymphocyte. B cell B lymphocyte Hematology One of the 2 major classes of lymphocytes, which comprises 30% of circulating lymphocytes and is concentrated in the follicular zones of lymphoid tissue–in contrast T cells is located in the deep cortex; B
cells are responsible for antibody production, a transformation evoked by interaction with the appropriate CD4 T-helper cells; Igs are responsible for specific defense against viruses and bacteria, immune surveillance–cytolysis of potentially
malignant 'self' cells, mediation of antibody-dependent cell cytotoxicity, allergic reactions, formation of antigen-antibody complexes, and production of cytokines; surface and cytoplasmic antigens indicate the degree of B cell
maturation and function; cytoplasmic IgM is present in pre-B cells and surface Ig in mature B lymphoctytes and plasma cells; complement receptors are seen in mature cells; B cell 'markers' include CD9, CD10, CD19, CD20, CD24, Fc
receptor, B1, BA-1, B4 Ia. See Pan B cell markers, Cf T cells. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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B-CHOP B-DNA B-DOPA B-E B-E amputation B-K B-lymphocyte B-lymphocyte subsets B-mode B-MOPP B-type natriuretic peptide B-type virus B-virus b.d b.d. |
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