In the treating immunosuppressed mice test, three doses of ZQE groups could increase the carbon clearance index, the weight ratios of spleen and thymus, serum hemolysin level, promote the secretion of IL-2, IL-4, and IFN-, and T-, B-lymphocyte
transformation rate by 1.
Anthera's clinical-stage programme includes a Phase II study of blisibimod (A-623), a selective antagonist of B-cell activating factor (BAFF, also known as B-lymphocyte
stimulator or BLyS), assessing its efficacy, safety and tolerability in patients with systemic lupus erythematosus.
SCID is a primary immune deficiency, whose defining characteristic is usually a severe defect in both the T- and B-lymphocyte
This mutation of the "cg" (for common gamma chain) gene on the X chromosome results in very low T-lymphocyte and NK-lymphocyte counts but the B-lymphocyte
count is high.
We believe that interfering antibodies started to emerge in our case after reduction of the CsA dose, concomitant increase in B-lymphocyte
Cryoglobulinemia is the main extra-hepatic manifestation of chronic hepatitis C, which is caused by a dysfunction of B-lymphocyte
and is immunochemically characterized by a cryoprecipitable immune complex formed by rheumatoid factor and IgG antibodies linked to HCV core antigen.
inhibits the biological activity of B-lymphocyte
stimulator (BLyS), a cytokine that is elevated in patients with SLE and other autoimmune diseases
The presence of activated B-lymphocytes
in the peripheral blood is a result of the first B-lymphocyte
response to foreign antigen, therefore the "OTHERS" parameter could potentially become a useful diagnostic tool in differentiating between infection and inflammation (1).
The discovery of the family of ligands and receptors, also known as BAFF, transformed the understanding of B-lymphocyte
selection, survival, activation, and homeostasis.
1737) describe a novel bioassay that identifies genotoxic effects by comparing cell proliferation kinetics between wild-type and DNA-repair-deficient mutant clones of the chicken DT40 B-lymphocyte
Distinction in the bone marrow of benign B-lymphocyte
precursors known as hematogones from neoplastic lymphoblasts of ALL is critical for disease management (in post-chemotherapy and post-bone marrow transplant regenerating marrow) (6,7).
LymphoStat-B is a human monoclonal antibody that specifically recognizes and inhibits the biological activity of B-lymphocyte
stimulator, or BLyS.