B-cell

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Related to B-cells: Plasma B cells

B-cell

a LYMPHOCYTE formed in the bone marrow of mammals that, after stimulation with a particular ANTIGEN, divides to produce daughter cells that manufacture large amounts of ANTIBODIES which are passed into the bloodstream.

B-cell (B-lymphocyte)

Type of white blood cell that produces antibodies.
Mentioned in: Multiple Myeloma
References in periodicals archive ?
4,6,7) These may harbour chronically activated B-cells that could act as APC, as regulators of local immune responses and as potential precursors of immunoglobulin (Ig)secreting plasma cells within the CNS compartment.
Poster 536 - Chemotherapy-Refractory Diffuse Large B-Cell Lymphomas (DLBCL) Are Effectively Killed by Ofatumumab-Induced Complement-Mediated Cytoxicity
Extensive clinical studies of ZEVALIN have confirmed high response rates and durable responses in patients with relapsed, refractory follicular or transformed B-cell NHL.
Learning of this, Edwards forged ahead with testing B-cell depletion in 20 people who have had rheumatoid arthritis for an average of 22 years and have failed to respond to conventional drugs.
The solution is to turn everything off and start up afresh - which in this case means using drugs to eliminate all the B-cells.
GA101 has been specifically designed as the first glycoengineered, type 2 anti-CD20 monoclonal antibody in development for B-cell malignancies.
The incidence is 8,100 to 12,500 new cases in the US per year and 85-95% of the cases are of B-cell origin.
In 1997, Rituxan was the first monoclonal antibody approved for cancer, when it was approved for treating relapsed or refractory low-grade or follicular CD20-positive, B-cell NHL.
Masayuki Noguchi, who works with Leonard, studied IL-7, which typically stimulates the growth of immature T-cells in the thymus and affects the development of a different white cell, the B-cell.
Non-progressing (including stable disease), low-grade, CD20-positive, B-cell NHL as a single agent after first-line CVP chemotherapy
solated b-cells, as well as islet clusters with lower than normal amount of non b-cells, do not release insulin in this biphasic manner, with no fine-tuning for intermediate concentrations of glucose in the blood.
HuMax-CD20 is a human antibody which is effective at binding to the CD20 molecule on B-cells.