B-cell receptors

B-cell re·cep·tors

(sel rĕ-sep'tŏrz)
A complex comprising a membrane-bound immunoglobulin molecule and two associated signal-transducing α- and β-chains.
References in periodicals archive ?
PRN1008 is a highly potent and selective inhibitor of Bruton tyrosine kinase (BTK), an enzyme that plays a major role in the signaling pathway running downstream from B cells to the B-cell receptors found on most white blood cells with the exception of T cells and plasma cells.
US-based Adaptive Biotechnologies, a specialist in combining sequencing and bioinformatics to profile T- and B-cell receptors of the adaptive immune system, has entered into a collaboration agreement with US-based biotechnology company Amgen to utilise Adaptive's NGS-based clonoSEQ Assay in the Phase 3 CANDOR study, sponsored by Amgen in collaboration with Janssen, comparing Kyprolis (carfilzomib), Darzalex (daratumumab), and dexamethasone with Kyrpolis and dexamethasone.
10x Genomics, a company focused on enabling the mastery of biology by accelerating genomic discovery, this week will launch new products for their Chromium Immune Repertoire Profiling Solution utilizing massively-parallel single cell RNA-seq (scRNA-seq) to sequence paired V(D)J B-cell receptors, together with unbiased gene expression for reading the immune-repertoire along with cell phenotype.
Adaptive Biotechnologies combines high-throughput sequencing and expert bioinformatics to profile T-cell and B-cell receptors.
This vaccine concept, using the proven, modern technology of baculovirus VLPs will enable enhanced cross linking of B-cell receptors and favour induction of B-cell responses against common epitopes essential for long-lasting cross recognition and protection.
Adaptive Biotechnologies combines high-throughput sequencing and expert bioinformatics to profile T-cell and B-cell receptors bringing its immunosequencing platform into laboratories around the world to drive groundbreaking research in cancer and other immune-mediated diseases.
Adaptive Biotechnologies is combines Next Generation Sequencing and expert bioinformatics to profile T-cell and B-cell receptors.
Adaptive Biotechnologies is in combining high-throughput sequencing and expert bioinformatics to profile T-cell and B-cell receptors.
Adaptive Biotechnologies is a specialist in combining high-throughput sequencing and bioinformatics to profile T-cell and B-cell receptors.
Adaptive Biotechnologies plans to launch additional research use only immunoSEQ Kits for B-cell receptors and other specific receptor loci, as well as to expand distribution internationally next year.