azurophil

(redirected from Azurophilic granules)

azurophil

 [azh-u´ro-fil]
a tissue constituent staining with azure or a similar blue aniline dye.

az·u·ro·phil

, azurophile (azh-ū'rō-fil, -fīl),
Staining readily with an azure dye, denoting especially the hyperchromatin and reddish purple granules of some blood cells.
[azure + G. philos, fond]

azurophil

/az·u·ro·phil/ (azh-u´ro-fil″) a tissue constituent staining with azure or a similar metachromatic thiazin dye.

azurophil

a substance that stains readily with an azure blue aniline dye. azurophilic, adj.

azurophil

adjective Referring to any substance or cell that stains with an azurophilic (blue aniline) dye—e.g., azurophilic cell, azurophilic granule.
 
noun Any substance or cell that stains with an azurophilic (blue aniline) dye—e.g., azurophilic cell, azurophilic granule.

az·u·ro·phil

, azurophile (azh'ŭr-ō-fil, -fīl)
Staining readily with an azure dye, denoting especially the hyperchromatin and reddish-purple granules (i.e., azurophilic granules) of certain blood cells.
[azure + G. philos, fond]

azurophil

a tissue constituent staining with azure or a similar metachromatic thiazine dye.
References in periodicals archive ?
Diagnosis can be made with a simple peripheral smear for the classic giant azurophilic granules, which are peroxidase-positive, in all granule-containing cells including the peripheral blood and bone marrow.
In humans, azurophilic granules can be differentiated into defensin-high and defensin-low [39].
In positive cases, 2 main fluorescent patterns will be detected in ethanol-fixed neutrophils: one that reacts with the azurophilic granules distributed throughout the cytoplasm (cytoplasmic pattern, called cANCA) and one that reacts only with antigens located in the cytoplasm surrounding the nucleus (perinuclear pattern, called pANCA).
Identification of cell abnormalities--such as the large azurophilic granules in toxic granulation, asynchronous maturation, micromegakaryocyte identification or quantitating variant lymphs--still requires a skilled human eye.
To the Editor: Large granular lymphocytic leukemia (LGLL) is a rare chronic clonal lymphoproliferative disease characterized by a persistent increase in large granular lymphocytes, which are large lymphocytes with a low nucleus to cytoplasm ratio and an abundant cytoplasm with azurophilic granules.
Electron microscopic studies suggest that these granules are formed by the fusion of azurophilic granules (9).
1,2) The appearance of TG is the result of an increase in acid mucosubstance in azurophilic granules, which stains more prominently than under normal circumstances.
It has been also observed that increased myeloperoxidase which is present in azurophilic granules of polymorphonuclear neutrophils, activity in periodontitis as compared to controls [3].
4, when viewed at a higher magnification, shows part of a polysomatic nucleus (PN) and several large globules slightly under-focused to show the superficial caps of densely azurophilic granules in the optical plane above the spheres.
The cytoplasm is clear, vacuolated and may contain one or two purple azurophilic granules at the poles.
Review of the peripheral blood smear noted blastlike cells with finely dispersed chromatin, prominent nucleoli, and fine cytoplasmic azurophilic granules (Figure 1, A through C).