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azelastine |
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azelastine /azel·as·tine/ (ah-zel´as-tēn″) a topical antihistamine used as the hydrochloride salt in the treatment of seasonal allergic rhinitis and allergic conjunctivitis. azelastine, an H1-selective antihistamine that also inhibits leukotriene and platelet activating factor (PAF) synthesis and release. indications This drug is used to treat seasonal allergic rhinitis and seasonal allergic conjunctivitis. contraindications Known hypersensitivity, acute asthma attacks, and lower respiratory tract disease prohibit this drug's use. adverse effects Side effects include sedation (more common with increased doses), increased drowsiness, weight increase, and myalgia. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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The active ingredient of Higuard azelastine hydrochloride exhibits anti-allergic effects by inhibiting and releasing leukotriens and histamine that cause allergy, relieving allergic symptoms including rhinitis (sneezing, runny and stuffy nose) and skin problems (urticaria, eczema, etc). Azelastine hydrochloride is a relatively selective histamine H1 antagonist/mast cell stabilizer and an inhibitor of the release of histamine and other mediators from cells involved in the allergic response. |
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