amastigote

(redirected from Axenic amastigotes)

Leish·man-Don·o·van bod·y

(līsh'măn don'ŏ-văn),
the intracytoplasmic, nonflagellated leishmanial form of certain intracellular parasites, such as species of Leishmania or the intracellular form of Trypanosoma cruzi; originally used for Leishmania donovani parasites in infected spleen or liver cells in kala azar.
Synonym(s): amastigote, L-D body

amastigote

/amas·ti·gote/ (ah-mas´tĭ-gōt) the nonflagellate, intracellular, morphologic stage in the development of certain hemoflagellates, resembling the typical adult form of Leishmania.

Leish·man-Don·o·van bod·y

(lēsh'măn don'ŏ-văn bod'ē)
The intracytoplasmic, nonflagellated leishmanial form of certain intracellular parasites, such as species of Leishmania or the intracellular form of Trypanosoma cruzi.
Synonym(s): amastigote.

Leishman,

Sir William Boog, Scottish surgeon, 1865-1926.
Leishmania - a genus of digenetic, asexual, protozoan flagellates.
Leishman chrome cells - basophilic granular leukocytes (basophils) observed in the circulating blood of some persons with blackwater fever.
Leishman stain - a polychromed eosin-methylene blue stain used in the examination of blood films.
Leishman-Donovan body - the intracytoplasmic, nonflagellated leishmanial form of certain intracellular parasites. Synonym(s): amastigote; L-D body
leishmaniasis - tropical disease that is spread by sandflies.

amastigote

an early stage in the life cycle of trypanosomes, found in invertebrates. The body is rounded and the flagellum is absent or represented by a short fibril. The kinetoplast is present.
References in periodicals archive ?
50] for AmpB and miltefosine against promastigotes and axenic amastigotes and distribution of LdMT SNPs in Leishmania infantum isolates and reference strains * [IC.
6]; Table) to AmpB and to miltefosine was studied in the in vitro promastigote and axenic amastigote form by determining the concentrations inhibiting parasite growth by 50% (1,2).
amazonensis axenic amastigotes using Rhodamine 123 (Rh 123) reagent following the protocol of manufacturer.
Antigenic differences between axenic amastigotes & promastigotes of Leishmania donovani.
Fortunately, in leishmaniasis a close correlation exists between the in vitro and in vivo results (2), because the test parasite is the disease-producing organism in human (amastigote) and these are maintained in vitro as axenic amastigotes and in macrophage culture presenting a semi- in vivo condition.
Axenic amastigotes system for drug screening has been used earlier (8-10).
Rapid fluorescent assay using Alamar Blue for screening drugs on axenic amastigotes of L.
Stage-specific activity of pentavalent antimony against Leishmania donovani axenic amastigotes.
DNA transformation of Leishmania infantum axenic amastigotes and their use in drug screening.