autoreceptor

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au·to·re·cep·tor

(au'tō-rē-sep'tŏr, tōr),
A site on a neuron that binds the neurotransmitter released by that neuron, which then regulates the neuron's activity.
[auto- + receptor]

autoreceptor

A neurotransmitter receptor located in the presynaptic terminal of the same neuron that produces the neurotransmitter. Autoreceptors have a higher affinity for the neurotransmitter than does the postsynaptic receptor, and thus have an autoregulatory function.

au·to·re·cep·tor

(aw'tō-rĕ-sep'tŏr)
A site on a neuron that binds the neurotransmitter released by that neuron, which then regulates the neuron's activity.

au·to·re·cep·tor

(aw'tō-rĕ-sep'tŏr)
A site on a neuron that binds the neurotransmitter released by that neuron, which then regulates the neuron's activity.
[auto- + receptor]
References in periodicals archive ?
iDAN cells display sophisticated neuronal properties including pacemaking firing activity, synaptic integration, activity-dependent dopamine release and D2 functional autoreceptors.
Cocaine supersensitivity and enhanced motivation for reward in mice lacking dopamine D2 autoreceptors.
Ginger facilitates cholinergic activity possibly due to blockade of muscarinic autoreceptors in rat stomach fundus.
For example, studies in animal models and clinical investigations have demonstrated that reducing the overall level of noradrenergic activity by stimulating presynaptic autoreceptors with alpha2-adrenergic agonists (e.
2]-adrenergic receptor agonists such as guanfacine act at noradrenergic autoreceptors to inhibit the firing of noradrenergic neurons, effectively inhibiting the release of brain norepinephrine.
It is thought that Vilazodone's partial 5-HTlA receptor agonist activity asserts an effect on these autoreceptors that could speed up the patient's response time.
Because of the important role of D2 autoreceptors in regulating dopamine synthesis, they aimed to examine whether subjects with the A1 allele have altered presynaptic dopamine function in the brain.
There is evidence of enhanced sensitivity of D2 autoreceptors to alterations by lead (Zuch et al.
Binding of serotonin to 5-HT1A autoreceptors located on serotonergic neurons, produces an inhibitory effect decreasing neuronal firing rate and serotonin release.
The histamine H3 receptor is predominantly expressed in the brain, and inverse agonists of the H3 receptor increase the synthesis and release of histamine through inhibition of presynaptic autoreceptors.
Two pages of color plates on dopamine autoreceptors and postsynaptic receptors are tipped-in.
We've found that the density of these dopamine autoreceptors is inversely related to an individual's interest in and desire for novel experiences," David Zald, associate professor of psychology and lead author of the study at the Vanderbilt Kennedy Center for Research on Human Development.
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