autoimmunity

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Related to Autoimmune reaction: Autoimmune disorders, autoimmune response

autoimmunity

 [aw″to-ĭ-mu´nĭ-te]
a condition characterized by a specific humoral or cell-mediated immune response against the constituents of the body's own tissues (autoantigens); it may result in hypersensitivity reactions or, if severe, in autoimmune disease.

au·to·im·mu·ni·ty

(aw'tō-i-myū'ni-tē),
In immunology, the condition in which one's own tissues are subject to deleterious effects of actions of the immune system, as in autoallergy and in autoimmune disease; specific humoral or cell-mediated immune response against the body's own tissues. Synonym(s): autoallergy

autoimmunity

/au·to·im·mu·ni·ty/ (-ĭ-mu´nĭ-te) a condition characterized by a specific humoral or cell-mediated immune response against the constituents of the body's own tissues (autoantigens); it may result in hypersensitivity reactions or, if severe, in autoimmune disease.

autoimmunity

[-imyo̅o̅′nitē]
an abnormal condition in which the body reacts against constituents of its own tissues. Autoimmunity may result in hypersensitivity and autoimmune disease. Also called acute immune disease. See also antibody-specific model, autoantibody, autoantigen, autoimmune disease.

autoimmunity

The reaction of a host organism’s immune system to self-antigens as if they were foreign. It is characterised by T-cell activation, clonal expansion and antibody production against tissues, cells and antigens, which results in autoimmune disease.

autoimmunity

Self immunity Immunology The reaction of an organism's immune system to self antigens as if they were non-self or foreign; like alloimmunity, autoimmunity is characterized by the activation of T cells, clonal expansion, and antibody production. See Anti-nuclear antibodies, Anti-receptor antibodies, Clonal anergy, Superantigen.

au·to·im·mu·ni·ty

(aw'tō-i-myū'ni-tē)
immunology The condition in which one's own tissues are subject to deleterious effects of the immune system, as in autoallergy and in autoimmune disease; immune response against the body's own tissues.
See: autoallergy

autoimmunity

a situation where the immunological defences of the body become sensitized to parts of the same body resulting in self-destruction in that area. In other words, ‘self ANTIGENS become mistaken for ‘foreign’ antigens, so setting up an IMMUNE RESPONSE. Such an occurrence is clearly dangerous and may be associated with ageing. An example is rheumatoid arthritis in humans.

Autoimmunity

A condition in which the body's immune system produces antibodies in response to its own tissues or blood components instead of foreign particles or microorganisms.
Mentioned in: AIDS, Hypoparathyroidism

autoimmunity

immunological reaction against self-tissue, to deleterious effect

autoimmunity,

n abnormal immune response where the body attacks its own tissue constituents. Also called
acute immune disease.

au·to·im·mu·ni·ty

(aw'tō-i-myū'ni-tē)
In immunology, the condition in which one's own tissues are subject to deleterious effects of actions of the immune system.

autoimmunity

a condition which may result in autoimmune disease.
References in periodicals archive ?
1,2) T-helper cells (CD4+ cells) play a crucial role in initiating autoimmune reactions.
He has argued for years that autism can be traced to an autoimmune reaction centred on the brain.
In people with celiac disease, these can trigger an autoimmune reaction that damages the villi, tiny projections lining the small intestine that absorb nutrients from food into the body.
In an autoimmune reaction, a person's antibodies and immune cells target healthy tissues, triggering an inflammatory response.
The method worked best when the infusions of CD8+ Treg cells were given at the same time that the animals were injected with a protein that triggered the arthritis-causing autoimmune reaction.
In most cases, the diabetes is diagnosed first--usually in childhood or adolescence--and concurrently or subsequently an autoimmune reaction may occur in the gastrointestinal tract (Br.
Urticaria can be acute, appearing suddenly as a result of an allergic or autoimmune reaction, and can last for hours, or up to one day before fading.
None of the adverse effects were dose limiting, and no patients developed an autoimmune reaction similar to Wegener's granulomatosis a systemic vasculitis that's associated with antibodies to proteinase 3.
Multiple sclerosis, for example, describes an autoimmune reaction against nerve cells, and rheumatoid arthritis denotes an attack against the connective tissue of joints.
Our goal is to demonstrate that once the autoimmune reaction is halted, early in the disease course, the remaining cells either regenerate or have enough cell mass and functionality remaining so that the disease progress is halted or cured.
Gluten can trigger an autoimmune reaction in the intestines of genetically susceptible people.
In clinical trials, patients with multiple sclerosis have reported dramatic improvements after receiving injections of a myelin protein, which seem to turn off the autoimmune reaction.

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