autoimmune sensorineural hearing loss


Also found in: Acronyms.

autoimmune sensorineural hearing loss

A condition characterised by idiopathic, rapidly progressive, bilateral sensorineural hearing loss, which improves with corticosteroids and immunosuppressants. It is more common in women age 20 to 50.

Clinical findings
Bilateral sensorineural hearing loss which develops over weeks to months, with fluctuating symptoms, reduction in speech discrimination scores; vestibular symptoms occur in half of patients, and include disequilibrium, ataxia, motion intolerance, positional vertigo, and episodic vertigo; up to half of patients complain of tinnitus and aural fullness, and up to one-third have systemic autoimmune disease—e.g., rheumatoid arthritis, ulcerative colitis, systemic lupus erythematosus and polyarteritis nodosa.
References in periodicals archive ?
ELISPOT determination of interferon-gamma T-cell frequencies in patients with autoimmune sensorineural hearing loss.
The diagnosis of autoimmune sensorineural hearing loss (AISNHL) is ascertained by the history, clinical findings, response to immunosuppressive medication, and an immunologic evaluation of the patient's serum.
In 1979, McCabe presented evidence of a distinct clinical entity called autoimmune sensorineural hearing loss.

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