autoimmunity

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Related to Autoantigens: Autoimmune reaction

autoimmunity

 [aw″to-ĭ-mu´nĭ-te]
a condition characterized by a specific humoral or cell-mediated immune response against the constituents of the body's own tissues (autoantigens); it may result in hypersensitivity reactions or, if severe, in autoimmune disease.

au·to·im·mu·ni·ty

(aw'tō-i-myū'ni-tē),
In immunology, the condition in which one's own tissues are subject to deleterious effects of actions of the immune system, as in autoallergy and in autoimmune disease; specific humoral or cell-mediated immune response against the body's own tissues. Synonym(s): autoallergy

autoimmunity

/au·to·im·mu·ni·ty/ (-ĭ-mu´nĭ-te) a condition characterized by a specific humoral or cell-mediated immune response against the constituents of the body's own tissues (autoantigens); it may result in hypersensitivity reactions or, if severe, in autoimmune disease.

autoimmunity

[-imyo̅o̅′nitē]
an abnormal condition in which the body reacts against constituents of its own tissues. Autoimmunity may result in hypersensitivity and autoimmune disease. Also called acute immune disease. See also antibody-specific model, autoantibody, autoantigen, autoimmune disease.

autoimmunity

The reaction of a host organism’s immune system to self-antigens as if they were foreign. It is characterised by T-cell activation, clonal expansion and antibody production against tissues, cells and antigens, which results in autoimmune disease.

autoimmunity

Self immunity Immunology The reaction of an organism's immune system to self antigens as if they were non-self or foreign; like alloimmunity, autoimmunity is characterized by the activation of T cells, clonal expansion, and antibody production. See Anti-nuclear antibodies, Anti-receptor antibodies, Clonal anergy, Superantigen.

au·to·im·mu·ni·ty

(aw'tō-i-myū'ni-tē)
immunology The condition in which one's own tissues are subject to deleterious effects of the immune system, as in autoallergy and in autoimmune disease; immune response against the body's own tissues.
See: autoallergy

autoimmunity

a situation where the immunological defences of the body become sensitized to parts of the same body resulting in self-destruction in that area. In other words, ‘self ANTIGENS become mistaken for ‘foreign’ antigens, so setting up an IMMUNE RESPONSE. Such an occurrence is clearly dangerous and may be associated with ageing. An example is rheumatoid arthritis in humans.

Autoimmunity

A condition in which the body's immune system produces antibodies in response to its own tissues or blood components instead of foreign particles or microorganisms.
Mentioned in: AIDS, Hypoparathyroidism

autoimmunity

immunological reaction against self-tissue, to deleterious effect

autoimmunity,

n abnormal immune response where the body attacks its own tissue constituents. Also called
acute immune disease.

au·to·im·mu·ni·ty

(aw'tō-i-myū'ni-tē)
In immunology, the condition in which one's own tissues are subject to deleterious effects of actions of the immune system.

autoimmunity

a condition which may result in autoimmune disease.
References in periodicals archive ?
In this context, much effort has been expended to induce tolerance to autoantigens as an alternative to current and usually global immunosuppressive treatments.
2006) A new model for an etiology of rheumatoid arthritis: smoking may trigger HLA-DR (shared epitope)-restricted immune reactions to autoantigens modified by citrullination.
The autoantibody repertoire in T1D was first investigated with an array of 87 autoantigens in a 96-well plate format.
Autoantigens, infectious toxins which in turn, are one of the reasons of lifting of concentration of antibodies of a class M and G at VKH syndrome can be the reason of rising of level of pro-inflammatory cytokines in a blood.
In pursuit of B-cell synovial autoantigens in rheumatoid arthritis: Confirmation of citrullinated fibrinogen, detection of vimentin, and introducing carbonic anhydrase as a possible new synovial autoantigen.
These complexes are thought to behave as autoantigens determining the formation of antibodies elicited against gliadin peptides and tTG.
It has been possible to prevent or to delay onset of experimental autoimmune diseases in a variety of animal systems by feeding selected autoantigens or peptide derivatives (45).
I suppose we may also learn to combine autoantigens, together with possible stimulation of beta cells in combination with drugs that promote beta-cell regeneration," he continued.
I suppose we may also learn to combine autoantigens, together with possible stimulation of beta-cells in combination with drugs that promote betacell regeneration," he continued.
This antibody cross-reacted with the lupus-associated autoantigens Ro and Sm in lupus patients.
They recognise major histocompatibility complex (MHC) molecules in association with autoantigens with high specificity.