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Autoantibody |
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autoantibody /au·to·an·ti·body/ (-an´ti-bod?e) an antibody formed in response to, and reacting against, an antigenic constituent of one's own tissues.
Autoantibody An antibody produced by the body in reaction to any of its own cells or cell products. Mentioned in: Antimyocardial Antibody Test, Antinuclear Antibody Test, Autoimmune Disorders, Cold Agglutinins Test, Myasthenia Gravis autoantibody, n an immunoglobulin produced by the immune system that is directed against one or more of the host's own proteins. Many autoimmune diseases in humans, most notably lupus erythematosus, are caused by such antibodies. autoantibody an antibody formed in response to, and reacting against, an antigenic constituent of the animal's own cells or tissues. autoantibody Immunology Any antibody produced by an organism against one of its own–self antigens. See Antibody, Hashimoto's thyroiditis, Lupus erythematosus, Myasthenia gravis, Rheumatoid arthritis. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Induction of cytokines and anti-cytokine autoantibodies in cerebrospinal fluid (CSF) during experimental bacterial meningitis. Its clinical manifestations are almost invariably accompanied by the presence of autoantibodies directed at a wide array of self-components, including cell-surface structures (surface proteins and phospholipids on lymphocytes) and intracellular molecules (DNA, histones, and RNA) (von Muhlen and Tan 1995). Autoimmune disease occurs when a response against a self-antigen(s) involving T cells, B cells, or autoantibodies induces injury systemically or against a particular organ. |
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