autoimmunity

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autoimmunity

 [aw″to-ĭ-mu´nĭ-te]
a condition characterized by a specific humoral or cell-mediated immune response against the constituents of the body's own tissues (autoantigens); it may result in hypersensitivity reactions or, if severe, in autoimmune disease.

au·to·im·mu·ni·ty

(aw'tō-i-myū'ni-tē),
In immunology, the condition in which one's own tissues are subject to deleterious effects of actions of the immune system, as in autoallergy and in autoimmune disease; specific humoral or cell-mediated immune response against the body's own tissues. Synonym(s): autoallergy

autoimmunity

/au·to·im·mu·ni·ty/ (-ĭ-mu´nĭ-te) a condition characterized by a specific humoral or cell-mediated immune response against the constituents of the body's own tissues (autoantigens); it may result in hypersensitivity reactions or, if severe, in autoimmune disease.

autoimmunity

[-imyo̅o̅′nitē]
an abnormal condition in which the body reacts against constituents of its own tissues. Autoimmunity may result in hypersensitivity and autoimmune disease. Also called acute immune disease. See also antibody-specific model, autoantibody, autoantigen, autoimmune disease.

autoimmunity

The reaction of a host organism’s immune system to self-antigens as if they were foreign. It is characterised by T-cell activation, clonal expansion and antibody production against tissues, cells and antigens, which results in autoimmune disease.

autoimmunity

Self immunity Immunology The reaction of an organism's immune system to self antigens as if they were non-self or foreign; like alloimmunity, autoimmunity is characterized by the activation of T cells, clonal expansion, and antibody production. See Anti-nuclear antibodies, Anti-receptor antibodies, Clonal anergy, Superantigen.

au·to·im·mu·ni·ty

(aw'tō-i-myū'ni-tē)
immunology The condition in which one's own tissues are subject to deleterious effects of the immune system, as in autoallergy and in autoimmune disease; immune response against the body's own tissues.
See: autoallergy

autoimmunity

a situation where the immunological defences of the body become sensitized to parts of the same body resulting in self-destruction in that area. In other words, ‘self ANTIGENS become mistaken for ‘foreign’ antigens, so setting up an IMMUNE RESPONSE. Such an occurrence is clearly dangerous and may be associated with ageing. An example is rheumatoid arthritis in humans.

Autoimmunity

A condition in which the body's immune system produces antibodies in response to its own tissues or blood components instead of foreign particles or microorganisms.
Mentioned in: AIDS, Hypoparathyroidism

autoimmunity

immunological reaction against self-tissue, to deleterious effect

autoimmunity,

n abnormal immune response where the body attacks its own tissue constituents. Also called
acute immune disease.

au·to·im·mu·ni·ty

(aw'tō-i-myū'ni-tē)
In immunology, the condition in which one's own tissues are subject to deleterious effects of actions of the immune system.

autoimmunity

a condition which may result in autoimmune disease.
References in periodicals archive ?
In common with other auto-immune diseases, inflammation is the main problem.
Like other auto-immune diseases, such as multiple sclerosis, sufferers have periods of attacks and remission.
Rosacea's actually an auto-immune disease and, like most auto-immune diseases, we don't actually know what causes it, but there's a very strong association with something called dysbiosis, a bacterial imbalance and overgrowth of the wrong kinds of bacteria in the gut, News.
Venus had suffered a tough first-round exit from the singles, losing to Russian Elena Vesnina, and her career has been hit by Sjogren's Syndrome, an auto-immune disease, which has left her lacking in energy.
She vows to play on for years to come, and Venus, herself battling Sjogren's syndrome - an auto-immune disease that effects energy levels - is full of admiration for her sister.
Sequenta's products will ultimately enable new paradigms in the treatment of diseases as diverse as infection, auto-immune disease and cancer by providing diagnostic, prognostic, and monitoring tests to enable better targeting of therapies to achieve better clinical outcomes.
A leading charity described the development as "great news" for people with the auto-immune disease, who currently have to undergo regular injections.
An estimated 646,000 people in the UK have rheumatoid arthritis, an auto-immune disease that attacks the joints.
Tocilizumab is being hailed as a major breakthrough in combating the crippling auto-immune disease rheumatoid arthritis (RA), which attacks the joints and is the biggest cause of UK disability, with 420,000 sufferers in England and Wales alone.
It's good for able-bodied people but I've had scleroderma for about 14 years, which is an auto-immune disease which affects your blood and connective tissues, so I've got deformed hands.
An auto-immune disease, lupus is a type of self-allergy in which the patient's immune system creates antibodies which rather than protecting the body from bacteria and viruses, instead attack the person's own body tissues.
Lupus is a frequent, life-threatening, chronic auto-immune disease which strikes up to 3 million people in the seven major developed countries (source: Datamonitor, 2007).