Austrian syndrome

Austrian syndrome

A clinical complex first described by R Austrian in 1957, which consists of a triad of Streptococcus pneumoniae infections—pneumonia, meningitis, and endocarditis—and ruptured aortic valve, which is typically seen in alcoholics aged 40 to 60 with hyposplenism who, despite adequate antibiotic therapy, often die (80% mortality).

Austrian syndrome

A term used for Pts–usually alcoholics–with pneumococcal pneumonia, meningitis, and endocarditis and ruptured aortic valve, who present with bacteremia and, despite adequate antibiotic therapy, have a high–80% mortality
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References in periodicals archive ?
Austrian syndrome is a rare clinical entity that involves Streptococcus pneumoniae leading to the triad of pneumonia, meningitis, and endocarditis.
2) At present, this triad is known as Austrian syndrome, in honor of Robert Austrian, who described eight cases of pneumococcal endocarditis complicated by aortic valve rupture and associated with meningitis.
The sequence of infection in Austrian syndrome is usually pneumonia followed by endocarditis or meningitis
Current data suggests that the best approach in treating patients with Austrian syndrome may be a combined medical and surgical intervention.
Austrian syndrome is a rare but serious clinical entity that is associated with a highly aggressive clinical course.
To the Editor: In 1957, an American internist reported the preference of Streptococcus pneumoniae for the aortic valve and its frequent association with meningitis and pneumonia 1), an association now known as Austrian syndrome.
One case of Austrian syndrome has been reported in the pediatric age group, in a 7-year-old girl in whom aortic valve endocarditis developed after pneumococcal meningitis infection (2).
We report a previously healthy adolescent with Austrian syndrome associated with pandemic (H1N1) 2009 infection.
Thus, Austrian syndrome should be considered in any patient with pandemic (H1N1) 2009 complicated by pneumococcal infection and a new heart murmur.

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