aurothioglucose

aurothioglucose /au·ro·thio·glu·cose/ (aw″ro-thi″o-gloo´kōs) a monovalent gold salt used in treating rheumatoid arthritis.

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aurothioglucose

[ôr′ōthī′ōglo̅o̅′kōs]

an organic gold compound used as a disease-modifying antirheumatoid drug.

indication It is prescribed for adjunctive treatment of adult and juvenile rheumatoid arthritis, but generally no longer considered first line therapy.

contraindications Severe uncontrolled diabetes, renal or hepatic dysfunction, a history of infectious hepatitis, hypertension, heart failure, systemic lupus erythematosus, agranulocytosis, hemorrhagic diathesis, pregnancy, urticaria, eczema, colitis, or known hypersensitivity to this drug prohibit its use.

adverse effects Among the most serious adverse effects are kidney and liver damage and allergic reactions. Dermatitis and lesions of mucous membranes are common.

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aurothioglucose [aw″ro-thi″o-gloo´kōs]

a gold preparation used in the treatment of early active rheumatoid arthritis (both adult and juvenile types) not controlled by nonsteroidal antiinflammatory drugs, rest, and physical therapy; administered intramuscularly.

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aurothioglucose

a gold preparation used in treating immune-mediated diseases such as pemphigus complex and rheumatoid arthritis. See also chrysotherapy.