Aurora kinase B

Aurora kinase B

An Aurora kinase encoded by AURKB on chromosome 17p13.1. It is the catalytic component of the chromosomal passenger complex (CPC), which is critical for the correct progression through and completion of mitosis. It phosphorylates the CPC subunits BIRC5/survivin, CDCA8/borealin and INCENP, the last of which leads to increased AURKB activity.
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